Explore IL-1R2/IL1R2/CD121b gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
| Target ID |
GM-T23347
|
| Target Name |
IL-1R2/IL1R2/CD121b
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7850
|
| Gene ID |
100033831 (Equus caballus), 101080961 (Felis catus), 117022 (Rattus norvegicus), 16178 (Mus musculus)
481330 (Canis lupus familiaris), 515700 (Bos taurus), 711638 (Macaca mulatta), 7850 (Homo sapiens)
|
| Target Alternative Names |
CD121 antigen-like family member B,CD121b,CDw121b,IL-1 type II receptor,IL-1R-2,IL-1R2,IL-1RII,IL-1RT-2,IL-1RT2,IL1R2,IL1R2c,IL1RB,Il1r-2,Il1r2,Interleukin-1 receptor beta (IL-1R-beta),Interleukin-1 receptor type 2,Interleukin-1 receptor type II
|
| Uniprot Accession |
P43303,P27931,P27930
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Amoebiasis, Human T-cell leukemia virus 1 infection, Prostate cancer, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000000288, ENSMUSG00000026073, ENSCAFG00845010877, ENSBTAG00000006343, ENSMMUG00000020739, ENSG00000115590
|
Pre-made viral vector of IL-1R2/IL1R2/CD121b cDNA Clones/ORF Plasmid
IL-1R2/IL1R2/CD121b siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7850 | Pre-made Human IL1R2/IL1RB/CD121b siRNA oligo Duplex | 7850 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117022 | Pre-made Rat Il1r2 siRNA oligo Duplex | 117022 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16178 | Pre-made Mouse Il1r2/CD121b/Il1r-2 siRNA oligo Duplex | 16178 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711638 | Pre-made Cynomolgus/Rhesus macaque IL1R2 siRNA oligo Duplex | 711638 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080961 | Pre-made Cat/Feline IL1R2 siRNA oligo Duplex | 101080961 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481330 | Pre-made Dog/Canine IL1R2 siRNA oligo Duplex | 481330 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515700 | Pre-made Bovines/Cattle IL1R2/IL-1R2 siRNA oligo Duplex | 515700 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033831 | Pre-made Equine/Horse IL1R2/IL-1RII siRNA oligo Duplex | 100033831 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1R2/IL1R2/CD121b antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23347-Ab | Human | Anti-Human IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T23347-Ab | Rat | Anti-Rat IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T23347-Ab | Mouse | Anti-Mouse IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T23347-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T23347-Ab | Cat/Feline | Anti-Cat/Feline IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T23347-Ab | Dog/Canine | Anti-Dog/Canine IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T23347-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T23347-Ab | Equine/Horse | Anti-Equine/Horse IL-1R2/IL1R2/CD121b monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-1R2/IL1R2/CD121b VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23347-Ag | Human | Human IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T23347-Ag | Rat | Rat IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T23347-Ag | Mouse | Mouse IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T23347-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T23347-Ag | Cat/Feline | Cat/Feline IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T23347-Ag | Dog/Canine | Dog/Canine IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T23347-Ag | Bovines/Cattle | Bovines/Cattle IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T23347-Ag | Equine/Horse | Equine/Horse IL-1R2/IL1R2/CD121b VLP (virus-like particle) | HEK293 | Products Developing |
