Explore Gelsolin/GSN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T23000
|
| Target Name |
Gelsolin/GSN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2934
|
| Gene ID |
100034186 (Equus caballus), 101088372 (Felis catus), 227753 (Mus musculus), 2934 (Homo sapiens)
296654 (Rattus norvegicus), 474819 (Canis lupus familiaris), 535077 (Bos taurus), 699705 (Macaca mulatta)
|
| Target Alternative Names |
GSN,Gsn,ADF,AGEL,AMYLD4
|
| Uniprot Accession |
Q28372,P13020,P06396,Q68FP1,Q3SX14
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Regulation of actin cytoskeleton
|
| Gene Ensembl |
ENSECAG00000018714, ENSMUSG00000026879, ENSG00000148180, ENSCAFG00845016093, ENSBTAG00000019915, ENSMMUG00000013020
|
| Target Classification |
|
Pre-made viral vector of Gelsolin/GSN cDNA Clones/ORF Plasmid
Gelsolin/GSN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2934 | Pre-made Human GSN/ADF/AGEL siRNA oligo Duplex | 2934 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296654 | Pre-made Rat Gsn siRNA oligo Duplex | 296654 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo227753 | Pre-made Mouse Gsn/ADF siRNA oligo Duplex | 227753 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699705 | Pre-made Cynomolgus/Rhesus macaque GSN siRNA oligo Duplex | 699705 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088372 | Pre-made Cat/Feline GSN siRNA oligo Duplex | 101088372 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474819 | Pre-made Dog/Canine GSN siRNA oligo Duplex | 474819 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535077 | Pre-made Bovines/Cattle GSN siRNA oligo Duplex | 535077 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034186 | Pre-made Equine/Horse GSN/ADF siRNA oligo Duplex | 100034186 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Gelsolin/GSN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23000-Ab | Human | Anti-Human Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T23000-Ab | Rat | Anti-Rat Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T23000-Ab | Mouse | Anti-Mouse Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T23000-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T23000-Ab | Cat/Feline | Anti-Cat/Feline Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T23000-Ab | Dog/Canine | Anti-Dog/Canine Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T23000-Ab | Bovines/Cattle | Anti-Bovines/Cattle Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T23000-Ab | Equine/Horse | Anti-Equine/Horse Gelsolin/GSN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Gelsolin/GSN VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23000-Ag | Human | Human Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T23000-Ag | Rat | Rat Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T23000-Ag | Mouse | Mouse Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T23000-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T23000-Ag | Cat/Feline | Cat/Feline Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T23000-Ag | Dog/Canine | Dog/Canine Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T23000-Ag | Bovines/Cattle | Bovines/Cattle Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T23000-Ag | Equine/Horse | Equine/Horse Gelsolin/GSN VLP (virus-like particle) | HEK293 | Products Developing |
