Explore MAdCAM1/MADCAM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T22655
|
| Target Name |
MAdCAM1/MADCAM1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8174
|
| Gene ID |
101089986 (Felis catus), 102149135 (Equus caballus), 17123 (Mus musculus), 485103 (Canis lupus familiaris)
527275 (Bos taurus), 54266 (Rattus norvegicus), 721034 (Macaca mulatta), 8174 (Homo sapiens)
|
| Target Alternative Names |
MACAM1,MADCAM1,MAdCAM-1,MAdCAM1,Madcam1,Mucosal addressin cell adhesion molecule 1,hMAdCAM-1
|
| Uniprot Accession |
Q61826,O70540,Q13477
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease from KEGG |
Cell adhesion molecules, Intestinal immune network for IgA production
|
| Gene Ensembl |
ENSECAG00000040001, ENSMUSG00000020310, ENSCAFG00845015287, ENSBTAG00000039355, ENSMMUG00000008589, ENSG00000099866
|
MAdCAM1/MADCAM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8174 | Pre-made Human MADCAM1/MACAM1 siRNA oligo Duplex | 8174 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54266 | Pre-made Rat Madcam1 siRNA oligo Duplex | 54266 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17123 | Pre-made Mouse Madcam1/MAdCAM-1 siRNA oligo Duplex | 17123 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721034 | Pre-made Cynomolgus/Rhesus macaque MADCAM1/MAdCAM-1 siRNA oligo Duplex | 721034 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089986 | Pre-made Cat/Feline MADCAM1 siRNA oligo Duplex | 101089986 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485103 | Pre-made Dog/Canine MADCAM1 siRNA oligo Duplex | 485103 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527275 | Pre-made Bovines/Cattle MADCAM1 siRNA oligo Duplex | 527275 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149135 | Pre-made Equine/Horse MADCAM1 siRNA oligo Duplex | 102149135 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAdCAM1/MADCAM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22655-Ab | Human | Anti-Human MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22655-Ab | Rat | Anti-Rat MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22655-Ab | Mouse | Anti-Mouse MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22655-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22655-Ab | Cat/Feline | Anti-Cat/Feline MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22655-Ab | Dog/Canine | Anti-Dog/Canine MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22655-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22655-Ab | Equine/Horse | Anti-Equine/Horse MAdCAM1/MADCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MAdCAM1/MADCAM1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22655-Ag | Human | Human MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T22655-Ag | Rat | Rat MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T22655-Ag | Mouse | Mouse MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T22655-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T22655-Ag | Cat/Feline | Cat/Feline MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T22655-Ag | Dog/Canine | Dog/Canine MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T22655-Ag | Bovines/Cattle | Bovines/Cattle MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T22655-Ag | Equine/Horse | Equine/Horse MAdCAM1/MADCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
