Explore Endoglin/CD105/ENG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
| Target ID |
GM-T22350
|
| Target Name |
Endoglin/CD105/ENG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2022
|
| Gene ID |
100070421 (Equus caballus), 101093216 (Felis catus), 13805 (Mus musculus), 2022 (Homo sapiens)
497010 (Rattus norvegicus), 609166 (Canis lupus familiaris), 615844 (Bos taurus), 706569 (Macaca mulatta)
|
| Target Alternative Names |
CD105,END,ENG,Endo,Endoglin,Eng,HHT1,ORW1,S-endoglin
|
| Uniprot Accession |
Q63961,P17813
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
Breast Cancer, breast cancer, Pre-eclampsia
|
| Gene Ensembl |
ENSECAG00000020173, ENSMUSG00000026814, ENSG00000106991, ENSCAFG00845005326, ENSBTAG00000008997, ENSMMUG00000002248
|
Pre-made viral vector of Endoglin/CD105/ENG cDNA Clones/ORF Plasmid
Endoglin/CD105/ENG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2022 | Pre-made Human ENG/END/HHT1 siRNA oligo Duplex | 2022 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497010 | Pre-made Rat Eng siRNA oligo Duplex | 497010 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13805 | Pre-made Mouse Eng/Endo/CD105 siRNA oligo Duplex | 13805 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706569 | Pre-made Cynomolgus/Rhesus macaque ENG siRNA oligo Duplex | 706569 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093216 | Pre-made Cat/Feline ENG siRNA oligo Duplex | 101093216 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609166 | Pre-made Dog/Canine ENG siRNA oligo Duplex | 609166 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615844 | Pre-made Bovines/Cattle ENG siRNA oligo Duplex | 615844 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070421 | Pre-made Equine/Horse ENG/CD105 siRNA oligo Duplex | 100070421 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Endoglin/CD105/ENG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22350-Ab | Human | Anti-Human Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22350-Ab | Rat | Anti-Rat Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22350-Ab | Mouse | Anti-Mouse Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22350-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22350-Ab | Cat/Feline | Anti-Cat/Feline Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22350-Ab | Dog/Canine | Anti-Dog/Canine Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22350-Ab | Bovines/Cattle | Anti-Bovines/Cattle Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22350-Ab | Equine/Horse | Anti-Equine/Horse Endoglin/CD105/ENG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Endoglin/CD105/ENG VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22350-Ag | Human | Human Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T22350-Ag | Rat | Rat Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T22350-Ag | Mouse | Mouse Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T22350-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T22350-Ag | Cat/Feline | Cat/Feline Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T22350-Ag | Dog/Canine | Dog/Canine Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T22350-Ag | Bovines/Cattle | Bovines/Cattle Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T22350-Ag | Equine/Horse | Equine/Horse Endoglin/CD105/ENG VLP (virus-like particle) | HEK293 | Products Developing |
