Explore FCGR2A/CD32a/CD32 gene products and cross-species
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Target
sublocation: Transmembrane Protein.
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
| Target ID |
GM-T22212
|
| Target Name |
FCGR2A/CD32a/CD32
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2212
|
| Gene ID |
2212 (Homo sapiens), 719996 (Macaca mulatta)
|
| Target Alternative Names |
CD32,CD32A,CD32a,CDw32,FCG2,FCGR2,FCGR2A,FCGR2A1,FGCR,Fc-gamma RII-a (Fc-gamma-RIIa,FcGR,FcRII-a),FcgammaRIIa,IGFR2,IgG Fc receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-a
|
| Uniprot Accession |
P12318
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Phagosome, Osteoclast differentiation, Platelet activation, Pathogenic Escherichia coli infection, Yersinia infection, Leishmaniasis, Staphylococcus aureus infection, Tuberculosis
|
| Gene Ensembl |
ENSG00000143226, ENSMMUG00000003775
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of FCGR2A/CD32a/CD32 cDNA Clones/ORF Plasmid
FCGR2A/CD32a/CD32 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2212 | Pre-made Human FCGR2A/CD32/FCG2 siRNA oligo Duplex | 2212 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719996 | Pre-made Cynomolgus/Rhesus macaque FCGR2A/CD32/FGCR siRNA oligo Duplex | 719996 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
FCGR2A/CD32a/CD32 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22212-Ab | Human | Anti-Human FCGR2A/CD32a/CD32 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22212-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FCGR2A/CD32a/CD32 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FCGR2A/CD32a/CD32 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22212-Ag | Human | Human FCGR2A/CD32a/CD32 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T22212-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FCGR2A/CD32a/CD32 VLP (virus-like particle) | HEK293 | Products Developing |
