Explore DRD1/D1R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T22118
|
| Target Name |
DRD1/D1R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1812
|
| Gene ID |
100058846 (Equus caballus), 101085098 (Felis catus), 13488 (Mus musculus), 1812 (Homo sapiens)
24316 (Rattus norvegicus), 281125 (Bos taurus), 489110 (Canis lupus familiaris), 697796 (Macaca mulatta)
|
| Target Alternative Names |
C030036C15Rik,D(1A) dopamine receptor,D1R,D1a,DADR,DRD1,DRD1A,Dopamine D1 receptor,Drd-1,Drd1,Drd1a,Gpcr15
|
| Uniprot Accession |
Q61616,P21728,P18901,Q95136,O77680
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Cocaine addiction, Amphetamine addiction, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000011620, ENSMUSG00000021478, ENSG00000184845, ENSBTAG00000047719, ENSCAFG00845000442, ENSMMUG00000005147
|
| Target Classification |
GPCR
|
Pre-made viral vector of DRD1/D1R cDNA Clones/ORF Plasmid
DRD1/D1R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1812 | Pre-made Human DRD1/D1R/DADR siRNA oligo Duplex | 1812 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24316 | Pre-made Rat Drd1/D1a/Drd-1 siRNA oligo Duplex | 24316 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13488 | Pre-made Mouse Drd1/Drd-1/Drd1a siRNA oligo Duplex | 13488 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697796 | Pre-made Cynomolgus/Rhesus macaque DRD1 siRNA oligo Duplex | 697796 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085098 | Pre-made Cat/Feline DRD1 siRNA oligo Duplex | 101085098 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489110 | Pre-made Dog/Canine DRD1 siRNA oligo Duplex | 489110 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281125 | Pre-made Bovines/Cattle DRD1 siRNA oligo Duplex | 281125 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058846 | Pre-made Equine/Horse DRD1 siRNA oligo Duplex | 100058846 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DRD1/D1R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22118-Ab | Human | Anti-Human DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22118-Ab | Rat | Anti-Rat DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22118-Ab | Mouse | Anti-Mouse DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22118-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22118-Ab | Cat/Feline | Anti-Cat/Feline DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22118-Ab | Dog/Canine | Anti-Dog/Canine DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22118-Ab | Bovines/Cattle | Anti-Bovines/Cattle DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22118-Ab | Equine/Horse | Anti-Equine/Horse DRD1/D1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DRD1/D1R VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22118-Ag | Human | Human DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T22118-Ag | Rat | Rat DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T22118-Ag | Mouse | Mouse DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T22118-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T22118-Ag | Cat/Feline | Cat/Feline DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T22118-Ag | Dog/Canine | Dog/Canine DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T22118-Ag | Bovines/Cattle | Bovines/Cattle DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T22118-Ag | Equine/Horse | Equine/Horse DRD1/D1R VLP (virus-like particle) | HEK293 | Products Developing |
