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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
| Target ID |
GM-T22032
|
| Target Name |
PTH2R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5746
|
| Gene ID |
100069338 (Equus caballus), 101094527 (Felis catus), 213527 (Mus musculus), 524064 (Bos taurus) 5746 (Homo sapiens), 609846 (Canis lupus familiaris), 710383 (Macaca mulatta), 81753 (Rattus norvegicus)
|
| Target Alternative Names |
PTH2 receptor,PTH2R,PTHR2,Parathyroid hormone 2 receptor,Pth2r,Pthr2
|
| Uniprot Accession |
Q91V95,P49190,P70555
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000014395, ENSMUSG00000025946, ENSBTAG00000011992, ENSG00000144407, ENSCAFG00845023795, ENSMMUG00000005295
|
| Target Classification |
GPCR
|
PTH2R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5746 | Pre-made Human PTH2R/PTHR2 siRNA oligo Duplex | 5746 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81753 | Pre-made Rat Pth2r/Pthr2 siRNA oligo Duplex | 81753 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo213527 | Pre-made Mouse Pth2r/Pthr2 siRNA oligo Duplex | 213527 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710383 | Pre-made Cynomolgus/Rhesus macaque PTH2R/PTHR2 siRNA oligo Duplex | 710383 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094527 | Pre-made Cat/Feline PTH2R siRNA oligo Duplex | 101094527 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609846 | Pre-made Dog/Canine PTH2R siRNA oligo Duplex | 609846 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524064 | Pre-made Bovines/Cattle PTH2R siRNA oligo Duplex | 524064 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069338 | Pre-made Equine/Horse PTH2R siRNA oligo Duplex | 100069338 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTH2R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T22032-Ab | Human | Anti-Human PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T22032-Ab | Rat | Anti-Rat PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T22032-Ab | Mouse | Anti-Mouse PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T22032-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T22032-Ab | Cat/Feline | Anti-Cat/Feline PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T22032-Ab | Dog/Canine | Anti-Dog/Canine PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T22032-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T22032-Ab | Equine/Horse | Anti-Equine/Horse PTH2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTH2R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T22032-Ag | Human | Human PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T22032-Ag | Rat | Rat PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T22032-Ag | Mouse | Mouse PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T22032-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T22032-Ag | Cat/Feline | Cat/Feline PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T22032-Ag | Dog/Canine | Dog/Canine PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T22032-Ag | Bovines/Cattle | Bovines/Cattle PTH2R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T22032-Ag | Equine/Horse | Equine/Horse PTH2R VLP (virus-like particle) | HEK293 | Products Developing |