Explore Alpha Galactosidase A/GLA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T21678
|
| Target Name |
Alpha Galactosidase A/GLA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2717
|
| Gene ID |
100060370 (Equus caballus), 101091428 (Felis catus), 11605 (Mus musculus), 119868482 (Canis lupus familiaris)
2717 (Homo sapiens), 363494 (Rattus norvegicus), 532742 (Bos taurus), 703129 (Macaca mulatta)
|
| Target Alternative Names |
GLA,Gla,Ags,GALA
|
| Uniprot Accession |
P51569,P06280
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series
|
| Gene Ensembl |
ENSECAG00000018500, ENSMUSG00000031266, ENSCAFG00845019636, ENSG00000102393, ENSBTAG00000019256, ENSMMUG00000019577
|
| Target Classification |
|
Alpha Galactosidase A/GLA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2717 | Pre-made Human GLA/GALA siRNA oligo Duplex | 2717 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363494 | Pre-made Rat Gla siRNA oligo Duplex | 363494 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11605 | Pre-made Mouse Gla/Ags siRNA oligo Duplex | 11605 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703129 | Pre-made Cynomolgus/Rhesus macaque GLA siRNA oligo Duplex | 703129 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091428 | Pre-made Cat/Feline GLA siRNA oligo Duplex | 101091428 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119868482 | Pre-made Dog/Canine GLA siRNA oligo Duplex | 119868482 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532742 | Pre-made Bovines/Cattle GLA siRNA oligo Duplex | 532742 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060370 | Pre-made Equine/Horse GLA siRNA oligo Duplex | 100060370 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Alpha Galactosidase A/GLA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T21678-Ab | Human | Anti-Human Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T21678-Ab | Rat | Anti-Rat Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T21678-Ab | Mouse | Anti-Mouse Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T21678-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T21678-Ab | Cat/Feline | Anti-Cat/Feline Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T21678-Ab | Dog/Canine | Anti-Dog/Canine Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T21678-Ab | Bovines/Cattle | Anti-Bovines/Cattle Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T21678-Ab | Equine/Horse | Anti-Equine/Horse Alpha Galactosidase A/GLA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Alpha Galactosidase A/GLA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T21678-Ag | Human | Human Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T21678-Ag | Rat | Rat Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T21678-Ag | Mouse | Mouse Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T21678-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T21678-Ag | Cat/Feline | Cat/Feline Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T21678-Ag | Dog/Canine | Dog/Canine Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T21678-Ag | Bovines/Cattle | Bovines/Cattle Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T21678-Ag | Equine/Horse | Equine/Horse Alpha Galactosidase A/GLA recombinant protein | Mammalian cell | Detail |
