Explore PDPK1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T20891
|
| Target Name |
PDPK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5170
|
| Gene ID |
100138102 (Bos taurus), 100630736 (Equus caballus), 101101686 (Felis catus), 18607 (Mus musculus)
479875 (Canis lupus familiaris), 5170 (Homo sapiens), 697523 (Macaca mulatta), 81745 (Rattus norvegicus)
|
| Target Alternative Names |
PDK1,PDPK1,PDPK2,PDPK2P,PRO0461,Pdk1,Pdpk1
|
| Uniprot Accession |
Q9Z2A0,O15530,Q6A1A2,O55173
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PPAR signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Axon guidance, Focal adhesion, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, Thyroid hormone signaling pathway, Insulin resistance, Aldosterone-regulated sodium reabsorption, Toxoplasmosis, Proteoglycans in cancer, Endometrial cancer, Prostate cancer, Non-small cell lung cancer, Choline metabolism in cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSBTAG00000034436, ENSECAG00000000626, ENSMUSG00000024122, ENSCAFG00845003792, ENSG00000140992, ENSMMUG00000011459
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of PDPK1 cDNA Clones/ORF Plasmid
PDPK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5170 | Pre-made Human PDPK1/PDK1/PDPK2 siRNA oligo Duplex | 5170 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81745 | Pre-made Rat Pdpk1 siRNA oligo Duplex | 81745 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18607 | Pre-made Mouse Pdpk1/Pdk1 siRNA oligo Duplex | 18607 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697523 | Pre-made Cynomolgus/Rhesus macaque PDPK1 siRNA oligo Duplex | 697523 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101686 | Pre-made Cat/Feline PDPK1 siRNA oligo Duplex | 101101686 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479875 | Pre-made Dog/Canine PDPK1 siRNA oligo Duplex | 479875 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100138102 | Pre-made Bovines/Cattle PDPK1 siRNA oligo Duplex | 100138102 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100630736 | Pre-made Equine/Horse PDPK1 siRNA oligo Duplex | 100630736 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDPK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T20891-Ab | Human | Anti-Human PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T20891-Ab | Rat | Anti-Rat PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T20891-Ab | Mouse | Anti-Mouse PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T20891-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T20891-Ab | Cat/Feline | Anti-Cat/Feline PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T20891-Ab | Dog/Canine | Anti-Dog/Canine PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T20891-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T20891-Ab | Equine/Horse | Anti-Equine/Horse PDPK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PDPK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T20891-Ag | Human | Human PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T20891-Ag | Rat | Rat PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T20891-Ag | Mouse | Mouse PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T20891-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T20891-Ag | Cat/Feline | Cat/Feline PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T20891-Ag | Dog/Canine | Dog/Canine PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T20891-Ag | Bovines/Cattle | Bovines/Cattle PDPK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T20891-Ag | Equine/Horse | Equine/Horse PDPK1 recombinant protein | Mammalian cell | Detail |
