Explore CHRM4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T20709
|
| Target Name |
CHRM4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1132
|
| Gene ID |
101088360 (Felis catus), 102147631 (Equus caballus), 1132 (Homo sapiens), 12672 (Mus musculus)
25111 (Rattus norvegicus), 512928 (Bos taurus), 574195 (Macaca mulatta), 611314 (Canis lupus familiaris)
|
| Target Alternative Names |
AChR M4,CHRM4,Chrm-4,Chrm4,HM4,M3R,M4,M4R,Muscarinic acetylcholine receptor M4,mm4 mAChR
|
| Uniprot Accession |
P08173,P32211,P08485,P41986
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Cholinergic synapse, Regulation of actin cytoskeleton
|
| Gene Ensembl |
ENSECAG00000023751, ENSG00000180720, ENSMUSG00000040495, ENSMMUG00000039412, ENSCAFG00845028143
|
| Target Classification |
GPCR
|
CHRM4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1132 | Pre-made Human CHRM4/HM4/M4R siRNA oligo Duplex | 1132 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25111 | Pre-made Rat Chrm4/M4 siRNA oligo Duplex | 25111 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12672 | Pre-made Mouse Chrm4/M4/Chrm-4 siRNA oligo Duplex | 12672 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574195 | Pre-made Cynomolgus/Rhesus macaque CHRM4/M3R siRNA oligo Duplex | 574195 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088360 | Pre-made Cat/Feline CHRM4 siRNA oligo Duplex | 101088360 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611314 | Pre-made Dog/Canine CHRM4 siRNA oligo Duplex | 611314 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512928 | Pre-made Bovines/Cattle CHRM4 siRNA oligo Duplex | 512928 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102147631 | Pre-made Equine/Horse CHRM4 siRNA oligo Duplex | 102147631 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CHRM4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T20709-Ab | Human | Anti-Human CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T20709-Ab | Rat | Anti-Rat CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T20709-Ab | Mouse | Anti-Mouse CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T20709-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T20709-Ab | Cat/Feline | Anti-Cat/Feline CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T20709-Ab | Dog/Canine | Anti-Dog/Canine CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T20709-Ab | Bovines/Cattle | Anti-Bovines/Cattle CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T20709-Ab | Equine/Horse | Anti-Equine/Horse CHRM4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CHRM4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T20709-Ag | Human | Human CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T20709-Ag | Rat | Rat CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T20709-Ag | Mouse | Mouse CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T20709-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T20709-Ag | Cat/Feline | Cat/Feline CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T20709-Ag | Dog/Canine | Dog/Canine CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T20709-Ag | Bovines/Cattle | Bovines/Cattle CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T20709-Ag | Equine/Horse | Equine/Horse CHRM4 VLP (virus-like particle) | HEK293 | Products Developing |
