STAT6 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore STAT6 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Target ID GM-T20585
Target Name STAT6
Gene Group ldentifer
(Target Gene ID in Homo species)
6778
Gene ID 100050053 (Equus caballus), 100142679 (Canis lupus familiaris), 101089873 (Felis catus), 20852 (Mus musculus)
353105 (Bos taurus), 362896 (Rattus norvegicus), 6778 (Homo sapiens), 714159 (Macaca mulatta)
Target Alternative Names D12S1644,HIES6,IL-4 Stat,IL-4-STAT,STAT6,STAT6B,STAT6C,Signal transducer and activator of transcription 6,Stat6
Uniprot Accession P52633,P42226
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer, Breast Cancer
Disease from KEGG JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Hepatitis B, Pathways in cancer, Inflammatory bowel disease
Gene Ensembl ENSECAG00000008705, ENSCAFG00845009828, ENSMUSG00000002147, ENSBTAG00000006335, ENSG00000166888, ENSMMUG00000017527


Pre-made viral vector of STAT6 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002008Human STAT6/D12S1644/IL-4-STAT Lentivirus plasmidNM_001178078.16778HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002008Human STAT6/D12S1644/IL-4-STAT Lentivirus particleNM_001178078.16778HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


STAT6 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo6778Pre-made Human STAT6/HIES6/STAT6B siRNA oligo Duplex6778HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo362896Pre-made Rat Stat6 siRNA oligo Duplex362896RatIn-vitro grade; in-vivo gradeDetail
pGMoligo20852Pre-made Mouse Stat6 siRNA oligo Duplex20852MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo714159Pre-made Cynomolgus/Rhesus macaque STAT6 siRNA oligo Duplex714159Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101089873Pre-made Cat/Feline STAT6 siRNA oligo Duplex101089873Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100142679Pre-made Dog/Canine STAT6 siRNA oligo Duplex100142679Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo353105Pre-made Bovines/Cattle STAT6 siRNA oligo Duplex353105Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100050053Pre-made Equine/Horse STAT6 siRNA oligo Duplex100050053Equine/HorseIn-vitro grade; in-vivo gradeDetail


STAT6 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T20585-AbHumanAnti-Human STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T20585-AbRatAnti-Rat STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T20585-AbMouseAnti-Mouse STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T20585-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T20585-AbCat/FelineAnti-Cat/Feline STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T20585-AbDog/CanineAnti-Dog/Canine STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T20585-AbBovines/CattleAnti-Bovines/Cattle STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T20585-AbEquine/HorseAnti-Equine/Horse STAT6 monoclonal antibodymabTherapeutics Target antibodyDetail


STAT6 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T20585-AgHumanHuman STAT6 recombinant proteinMammalian cellDetail
GM-Tg-rg-T20585-AgRatRat STAT6 recombinant proteinMammalian cellDetail
GM-Tg-mg-T20585-AgMouseMouse STAT6 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T20585-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque STAT6 recombinant proteinMammalian cellDetail
GM-Tg-felg-T20585-AgCat/FelineCat/Feline STAT6 recombinant proteinMammalian cellDetail
GM-Tg-cang-T20585-AgDog/CanineDog/Canine STAT6 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T20585-AgBovines/CattleBovines/Cattle STAT6 recombinant proteinMammalian cellDetail
GM-Tg-equg-T20585-AgEquine/HorseEquine/Horse STAT6 recombinant proteinMammalian cellDetail