Explore EML4/EMAP-4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T20296
|
| Target Name |
EML4/EMAP-4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
27436
|
| Gene ID |
100053784 (Equus caballus), 101094586 (Felis catus), 27436 (Homo sapiens), 313861 (Rattus norvegicus)
483048 (Canis lupus familiaris), 540187 (Bos taurus), 715091 (Macaca mulatta), 78798 (Mus musculus)
|
| Target Alternative Names |
4930443C24Rik,C2orf2,ELP120,EMAP-4,EMAPL4,EML4,Echinoderm microtubule-associated protein-like 4,Eml4,ROPP120,Restrictedly overexpressed proliferation-associated protein,Ropp 120
|
| Uniprot Accession |
Q9HC35,Q3UMY5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Pathways in cancer, Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSECAG00000007410, ENSG00000143924, ENSCAFG00845025729, ENSBTAG00000010935, ENSMMUG00000016277, ENSMUSG00000032624
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of EML4/EMAP-4 cDNA Clones/ORF Plasmid
EML4/EMAP-4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27436 | Pre-made Human EML4/C2orf2/ELP120 siRNA oligo Duplex | 27436 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313861 | Pre-made Rat Eml4 siRNA oligo Duplex | 313861 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo78798 | Pre-made Mouse Eml4/4930443C24Rik siRNA oligo Duplex | 78798 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715091 | Pre-made Cynomolgus/Rhesus macaque EML4 siRNA oligo Duplex | 715091 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094586 | Pre-made Cat/Feline EML4 siRNA oligo Duplex | 101094586 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483048 | Pre-made Dog/Canine EML4 siRNA oligo Duplex | 483048 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540187 | Pre-made Bovines/Cattle EML4 siRNA oligo Duplex | 540187 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053784 | Pre-made Equine/Horse EML4 siRNA oligo Duplex | 100053784 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EML4/EMAP-4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T20296-Ab | Human | Anti-Human EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T20296-Ab | Rat | Anti-Rat EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T20296-Ab | Mouse | Anti-Mouse EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T20296-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T20296-Ab | Cat/Feline | Anti-Cat/Feline EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T20296-Ab | Dog/Canine | Anti-Dog/Canine EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T20296-Ab | Bovines/Cattle | Anti-Bovines/Cattle EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T20296-Ab | Equine/Horse | Anti-Equine/Horse EML4/EMAP-4 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EML4/EMAP-4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T20296-Ag | Human | Human EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T20296-Ag | Rat | Rat EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T20296-Ag | Mouse | Mouse EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T20296-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T20296-Ag | Cat/Feline | Cat/Feline EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T20296-Ag | Dog/Canine | Dog/Canine EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T20296-Ag | Bovines/Cattle | Bovines/Cattle EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T20296-Ag | Equine/Horse | Equine/Horse EML4/EMAP-4 recombinant protein | Mammalian cell | Detail |
