CD122/IL-2RB/IL2RB Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore CD122/IL-2RB/IL2RB gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. [provided by RefSeq, Sep 2016]

Target ID GM-T19579
Target Name CD122/IL-2RB/IL2RB
Gene Group ldentifer
(Target Gene ID in Homo species)
3560
Gene ID 100069676 (Equus caballus), 101092622 (Felis catus), 104968644 (Bos taurus), 16185 (Mus musculus)
25746 (Rattus norvegicus), 3560 (Homo sapiens), 403439 (Canis lupus familiaris), 696331 (Macaca mulatta)
Target Alternative Names CD122,High affinity IL-2 receptor subunit beta,IL-15Rbeta,IL-2 receptor subunit beta,IL-2R subunit beta,IL-2RB,IL15RB,IL15Rbeta,IL2RB,IL2RBC,IMD63,Il-2/15Rbeta,Il-2Rbeta,Il2rb,Interleukin-15 receptor subunit beta,Interleukin-2 receptor subunit beta,P70-75,p70,p70-75 (p75)
Uniprot Accession P16297,P26896,P14784
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target
Disease cancer
Disease from KEGG Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Measles, Human T-cell leukemia virus 1 infection, Pathways in cancer
Gene Ensembl ENSECAG00000016033, ENSBTAG00000016345, ENSMUSG00000068227, ENSG00000100385, ENSCAFG00845007511, ENSMMUG00000005417
Target Classification Cytokine Receptor, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


Pre-made viral vector of CD122/IL-2RB/IL2RB cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMAP000140Human IL2RB/CD122/P70-75 Adenovirus plasmidBC0256913560HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAP000140Human IL2RB/CD122/P70-75 Adenovirus particleBC0256913560HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail


CD122/IL-2RB/IL2RB siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3560Pre-made Human IL2RB/CD122/IMD63 siRNA oligo Duplex3560HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25746Pre-made Rat Il2rb/IL2RBC siRNA oligo Duplex25746RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16185Pre-made Mouse Il2rb/p70/CD122 siRNA oligo Duplex16185MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo696331Pre-made Cynomolgus/Rhesus macaque IL2RB siRNA oligo Duplex696331Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092622Pre-made Cat/Feline IL2RB siRNA oligo Duplex101092622Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403439Pre-made Dog/Canine IL2RB siRNA oligo Duplex403439Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo104968644Pre-made Bovines/Cattle IL2RB siRNA oligo Duplex104968644Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100069676Pre-made Equine/Horse IL2RB siRNA oligo Duplex100069676Equine/HorseIn-vitro grade; in-vivo gradeDetail


CD122/IL-2RB/IL2RB antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T19579-AbHumanAnti-Human CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T19579-AbRatAnti-Rat CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T19579-AbMouseAnti-Mouse CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T19579-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T19579-AbCat/FelineAnti-Cat/Feline CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T19579-AbDog/CanineAnti-Dog/Canine CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T19579-AbBovines/CattleAnti-Bovines/Cattle CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T19579-AbEquine/HorseAnti-Equine/Horse CD122/IL-2RB/IL2RB monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


CD122/IL-2RB/IL2RB VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T19579-AgHumanHuman CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T19579-AgRatRat CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T19579-AgMouseMouse CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T19579-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T19579-AgCat/FelineCat/Feline CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T19579-AgDog/CanineDog/Canine CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T19579-AgBovines/CattleBovines/Cattle CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T19579-AgEquine/HorseEquine/Horse CD122/IL-2RB/IL2RB VLP (virus-like particle)HEK293Products Developing