ADCY5/AC5 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
| Target ID | GM-T19531 |
| Target Name | ADCY5/AC5 |
|
Gene Group ldentifer （Target Gene ID in Homo species) |
111 |
| Gene ID |
100070498 (Equus caballus), 101100749 (Felis catus), 111 (Homo sapiens), 224129 (Mus musculus) 403859 (Canis lupus familiaris), 505740 (Bos taurus), 64532 (Rattus norvegicus), 715897 (Macaca mulatta) |
| Target Alternative Names | ADCY5,Adcy5,AC5,FDFM,DSKOD,Ac5 |
| Uniprot Accession | O95622,P84309,P30803,Q04400 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | |
| Disease from KEGG | Metabolic pathways, Endocrine resistance, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, Phospholipase D signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Ovarian steroidogenesis, Melanogenesis, Thyroid hormone synthesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion, Relaxin signaling pathway, Cortisol synthesis and secretion, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Growth hormone synthesis, secretion and action, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion, Cocaine addiction, Amphetamine addiction, Morphine addiction, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Pathways in cancer, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy |
| Gene Ensembl | ENSECAG00000009948, ENSG00000173175, ENSMUSG00000022840, ENSCAFG00845024171, ENSBTAG00000018777, ENSMMUG00000002230 |
| Target Classification |
ADCY5/AC5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|---|---|---|---|---|
| pGMoligo111 | Pre-made Human ADCY5/AC5/FDFM siRNA oligo Duplex | 111 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64532 | Pre-made Rat Adcy5 siRNA oligo Duplex | 64532 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo224129 | Pre-made Mouse Adcy5/Ac5 siRNA oligo Duplex | 224129 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715897 | Pre-made Cynomolgus/Rhesus macaque ADCY5 siRNA oligo Duplex | 715897 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100749 | Pre-made Cat/Feline ADCY5 siRNA oligo Duplex | 101100749 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403859 | Pre-made Dog/Canine ADCY5 siRNA oligo Duplex | 403859 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505740 | Pre-made Bovines/Cattle ADCY5 siRNA oligo Duplex | 505740 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070498 | Pre-made Equine/Horse ADCY5 siRNA oligo Duplex | 100070498 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADCY5/AC5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|---|---|---|---|---|
| GM-Tg-hg-T19531-Ab | Human | Anti-Human ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T19531-Ab | Rat | Anti-Rat ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T19531-Ab | Mouse | Anti-Mouse ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T19531-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T19531-Ab | Cat/Feline | Anti-Cat/Feline ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T19531-Ab | Dog/Canine | Anti-Dog/Canine ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T19531-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T19531-Ab | Equine/Horse | Anti-Equine/Horse ADCY5/AC5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADCY5/AC5 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|---|---|---|---|
| GM-Tg-hg-T19531-Ag | Human | Human ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T19531-Ag | Rat | Rat ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T19531-Ag | Mouse | Mouse ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T19531-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T19531-Ag | Cat/Feline | Cat/Feline ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T19531-Ag | Dog/Canine | Dog/Canine ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T19531-Ag | Bovines/Cattle | Bovines/Cattle ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T19531-Ag | Equine/Horse | Equine/Horse ADCY5/AC5 VLP (virus-like particle) | HEK293 | Products Developing |