Explore Kv1.2/KCNA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T19492
|
| Target Name |
Kv1.2/KCNA2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3737
|
| Gene ID |
100058705 (Equus caballus), 101083868 (Felis catus), 16490 (Mus musculus), 25468 (Rattus norvegicus) 3737 (Homo sapiens), 404022 (Canis lupus familiaris), 539608 (Bos taurus), 702126 (Macaca mulatta)
|
| Target Alternative Names |
Akr6a4,BK2,DEE32,EIEE32,Gm10672,HBK5,HK4,HUKIV,KCNA2,KV1.2,Kca1-2,Kcna2,Kv1.2,MK2,Mk-2,NGK1,Potassium voltage-gated channel subfamily A member 2,RBK2,Voltage-gated K(+) channel HuKIV,Voltage-gated potassium channel HBK5,Voltage-gated potassium channel subunit Kv1.2
|
| Uniprot Accession |
P63141,P63142,P16389,Q28293
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000003066, ENSMUSG00000040724, ENSG00000177301, ENSCAFG00845001930, ENSBTAG00000015459, ENSMMUG00000054017
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of Kv1.2/KCNA2 cDNA Clones/ORF Plasmid
Kv1.2/KCNA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3737 | Pre-made Human KCNA2/HK4/MK2 siRNA oligo Duplex | 3737 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25468 | Pre-made Rat Kcna2/BK2/NGK1 siRNA oligo Duplex | 25468 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16490 | Pre-made Mouse Kcna2/Mk-2/Kv1.2 siRNA oligo Duplex | 16490 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702126 | Pre-made Cynomolgus/Rhesus macaque KCNA2 siRNA oligo Duplex | 702126 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083868 | Pre-made Cat/Feline KCNA2 siRNA oligo Duplex | 101083868 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404022 | Pre-made Dog/Canine KCNA2 siRNA oligo Duplex | 404022 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539608 | Pre-made Bovines/Cattle KCNA2 siRNA oligo Duplex | 539608 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058705 | Pre-made Equine/Horse KCNA2 siRNA oligo Duplex | 100058705 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Kv1.2/KCNA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19492-Ab | Human | Anti-Human Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T19492-Ab | Rat | Anti-Rat Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T19492-Ab | Mouse | Anti-Mouse Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T19492-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T19492-Ab | Cat/Feline | Anti-Cat/Feline Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T19492-Ab | Dog/Canine | Anti-Dog/Canine Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T19492-Ab | Bovines/Cattle | Anti-Bovines/Cattle Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T19492-Ab | Equine/Horse | Anti-Equine/Horse Kv1.2/KCNA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Kv1.2/KCNA2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19492-Ag | Human | Human Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T19492-Ag | Rat | Rat Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T19492-Ag | Mouse | Mouse Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T19492-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T19492-Ag | Cat/Feline | Cat/Feline Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T19492-Ag | Dog/Canine | Dog/Canine Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T19492-Ag | Bovines/Cattle | Bovines/Cattle Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T19492-Ag | Equine/Horse | Equine/Horse Kv1.2/KCNA2 VLP (virus-like particle) | HEK293 | Products Developing |