IL-21R/IL21R/CD360 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore IL-21R/IL21R/CD360 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]

Pre-made viral vector of IL-21R/IL21R/CD360 cDNA Clones/ORF Plasmid

IL-21R/IL21R/CD360 siRNA/miRNA/oligo for RNA interfence (RNAi)

IL-21R/IL21R/CD360 antibody/GMab

IL-21R/IL21R/CD360 VLP (virus-like particle)/protein