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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T19244
|
| Target Name |
CYP2C9
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1559
|
| Gene ID |
1559 (Homo sapiens)
|
| Target Alternative Names |
(R)-limonene 6-monooxygenase,(S)-limonene 6-monooxygenase,(S)-limonene 7-monooxygenase,CPC9,CYP2C,CYP2C10,CYP2C9,CYPIIC9,Cholesterol 25-hydroxylase,Cytochrome P-450MP,Cytochrome P450 2C9,Cytochrome P450 MP-4,Cytochrome P450 MP-8,Cytochrome P450 PB-1,P450-2C9,P450IIC9,S-mephenytoin 4-hydroxylase
|
| Uniprot Accession |
P11712
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Serotonergic synapse, Chemical carcinogenesis - DNA adducts, Lipid and atherosclerosis, Arachidonic acid metabolism, Linoleic acid metabolism, Retinol metabolism, Drug metabolism - cytochrome P450
|
| Gene Ensembl |
ENSG00000138109
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CYP2C9 cDNA Clones/ORF Plasmid
CYP2C9 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1559 | Pre-made Human CYP2C9/CPC9/CYP2C siRNA oligo Duplex | 1559 | Human | In-vitro grade; in-vivo grade | Detail |
CYP2C9 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19244-Ab | Human | Anti-Human CYP2C9 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CYP2C9 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19244-Ag | Human | Human CYP2C9 VLP (virus-like particle) | HEK293 | Products Developing |