SLC46A1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SLC46A1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

Target ID GM-T19229
Target Name SLC46A1
Gene Group ldentifer
(Target Gene ID in Homo species)
113235
Gene ID 101100096 (Felis catus), 113235 (Homo sapiens), 303333 (Rattus norvegicus), 491166 (Canis lupus familiaris)
511097 (Bos taurus), 52466 (Mus musculus), 708727 (Macaca mulatta)
Target Alternative Names 1110002C08Rik,D11Ertd18e,G21,HCP1,Heme carrier protein 1,HsPCFT,PCFT,PCFT/HCP1,Pcft,Proton-coupled folate transporter,RGD1309472,SLC46A1,Slc46a1,Solute carrier family 46 member 1,TRPE,hPCFT,rPCFT
Uniprot Accession Q96NT5,Q5EBA8,Q05B81,Q6PEM8
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease from KEGG Antifolate resistance, Vitamin digestion and absorption, Mineral absorption
Gene Ensembl ENSG00000076351, ENSCAFG00845007379, ENSBTAG00000002817, ENSMUSG00000020829, ENSMMUG00000019151


Pre-made viral vector of SLC46A1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLPm003784Mouse Slc46a1/1110002C08Rik/D11Ertd18e Lentivirus plasmidNM_02674052466MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm003784Mouse Slc46a1/1110002C08Rik/D11Ertd18e Lentivirus particleNM_02674052466MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


SLC46A1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo113235Pre-made Human SLC46A1/G21/HCP1 siRNA oligo Duplex113235HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo303333Pre-made Rat Slc46a1/rPCFT/RGD1309472 siRNA oligo Duplex303333RatIn-vitro grade; in-vivo gradeDetail
pGMoligo52466Pre-made Mouse Slc46a1/HCP1/Pcft siRNA oligo Duplex52466MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo708727Pre-made Cynomolgus/Rhesus macaque SLC46A1 siRNA oligo Duplex708727Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101100096Pre-made Cat/Feline SLC46A1 siRNA oligo Duplex101100096Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo491166Pre-made Dog/Canine SLC46A1 siRNA oligo Duplex491166Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo511097Pre-made Bovines/Cattle SLC46A1/TRPE siRNA oligo Duplex511097Bovines/CattleIn-vitro grade; in-vivo gradeDetail


SLC46A1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T19229-AbHumanAnti-Human SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T19229-AbRatAnti-Rat SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T19229-AbMouseAnti-Mouse SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T19229-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T19229-AbCat/FelineAnti-Cat/Feline SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T19229-AbDog/CanineAnti-Dog/Canine SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T19229-AbBovines/CattleAnti-Bovines/Cattle SLC46A1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


SLC46A1 VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T19229-AgHumanHuman SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T19229-AgRatRat SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T19229-AgMouseMouse SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T19229-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T19229-AgCat/FelineCat/Feline SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T19229-AgDog/CanineDog/Canine SLC46A1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T19229-AgBovines/CattleBovines/Cattle SLC46A1 VLP (virus-like particle)HEK293Products Developing