Explore PTGER4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T18876
|
| Target Name |
PTGER4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5734
|
| Gene ID |
100053208 (Equus caballus), 100169968 (Felis catus), 19219 (Mus musculus), 282331 (Bos taurus)
403589 (Canis lupus familiaris), 5734 (Homo sapiens), 695220 (Macaca mulatta), 84023 (Rattus norvegicus)
|
| Target Alternative Names |
EP4,EP4R,PGE receptor EP4 subtype,PGE2 receptor EP4 subtype,PTGER4,Prostaglandin E2 receptor EP4 subtype,Prostanoid EP4 receptor,Ptger,Ptger4,Ptgerep4,ep4
|
| Uniprot Accession |
P32240,Q8MJ08,P35408,P43114
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels, Renin secretion, Human cytomegalovirus infection, Human papillomavirus infection, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000011145, ENSMUSG00000039942, ENSBTAG00000014972, ENSCAFG00845002906, ENSG00000171522, ENSMMUG00000016167
|
| Target Classification |
GPCR, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of PTGER4 cDNA Clones/ORF Plasmid
PTGER4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5734 | Pre-made Human PTGER4/EP4/EP4R siRNA oligo Duplex | 5734 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84023 | Pre-made Rat Ptger4/EP4/Ptger siRNA oligo Duplex | 84023 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19219 | Pre-made Mouse Ptger4/EP4/Ptgerep4 siRNA oligo Duplex | 19219 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695220 | Pre-made Cynomolgus/Rhesus macaque PTGER4 siRNA oligo Duplex | 695220 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100169968 | Pre-made Cat/Feline PTGER4/EP4 siRNA oligo Duplex | 100169968 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403589 | Pre-made Dog/Canine PTGER4 siRNA oligo Duplex | 403589 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282331 | Pre-made Bovines/Cattle PTGER4/ep4 siRNA oligo Duplex | 282331 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053208 | Pre-made Equine/Horse PTGER4 siRNA oligo Duplex | 100053208 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTGER4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T18876-Ab | Human | Anti-Human PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T18876-Ab | Rat | Anti-Rat PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T18876-Ab | Mouse | Anti-Mouse PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T18876-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T18876-Ab | Cat/Feline | Anti-Cat/Feline PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T18876-Ab | Dog/Canine | Anti-Dog/Canine PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T18876-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T18876-Ab | Equine/Horse | Anti-Equine/Horse PTGER4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PTGER4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T18876-Ag | Human | Human PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T18876-Ag | Rat | Rat PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T18876-Ag | Mouse | Mouse PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T18876-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T18876-Ag | Cat/Feline | Cat/Feline PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T18876-Ag | Dog/Canine | Dog/Canine PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T18876-Ag | Bovines/Cattle | Bovines/Cattle PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T18876-Ag | Equine/Horse | Equine/Horse PTGER4 VLP (virus-like particle) | HEK293 | Products Developing |
