Explore MGLL/MAGL gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
| Target ID |
GM-T18664
|
| Target Name |
MGLL/MAGL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11343
|
| Gene ID |
100053785 (Equus caballus), 100429242 (Macaca mulatta), 101089928 (Felis catus), 11343 (Homo sapiens)
23945 (Mus musculus), 29254 (Rattus norvegicus), 476511 (Canis lupus familiaris), 505290 (Bos taurus)
|
| Target Alternative Names |
HU-K5,HUK5,Lysophospholipase homolog,Lysophospholipase-like,MAGL,MGL,MGLL,Magl,Mgl,Mgll,Monoacylglycerol lipase (MAGL),Monoglyceride lipase
|
| Uniprot Accession |
Q99685,O35678,Q8R431
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Regulation of lipolysis in adipocytes
|
| Gene Ensembl |
ENSECAG00000007658, ENSMMUG00000000168, ENSG00000074416, ENSMUSG00000033174, ENSCAFG00845017684, ENSBTAG00000018248
|
Pre-made viral vector of MGLL/MAGL cDNA Clones/ORF Plasmid
MGLL/MAGL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11343 | Pre-made Human MGLL/MGL/HUK5 siRNA oligo Duplex | 11343 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29254 | Pre-made Rat Mgll/MAGL siRNA oligo Duplex | 29254 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23945 | Pre-made Mouse Mgll/Mgl/Magl siRNA oligo Duplex | 23945 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429242 | Pre-made Cynomolgus/Rhesus macaque MGLL siRNA oligo Duplex | 100429242 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089928 | Pre-made Cat/Feline MGLL siRNA oligo Duplex | 101089928 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476511 | Pre-made Dog/Canine MGLL siRNA oligo Duplex | 476511 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505290 | Pre-made Bovines/Cattle MGLL siRNA oligo Duplex | 505290 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053785 | Pre-made Equine/Horse MGLL siRNA oligo Duplex | 100053785 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MGLL/MAGL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T18664-Ab | Human | Anti-Human MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T18664-Ab | Rat | Anti-Rat MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T18664-Ab | Mouse | Anti-Mouse MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T18664-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T18664-Ab | Cat/Feline | Anti-Cat/Feline MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T18664-Ab | Dog/Canine | Anti-Dog/Canine MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T18664-Ab | Bovines/Cattle | Anti-Bovines/Cattle MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T18664-Ab | Equine/Horse | Anti-Equine/Horse MGLL/MAGL monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MGLL/MAGL recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T18664-Ag | Human | Human MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T18664-Ag | Rat | Rat MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T18664-Ag | Mouse | Mouse MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T18664-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T18664-Ag | Cat/Feline | Cat/Feline MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T18664-Ag | Dog/Canine | Dog/Canine MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T18664-Ag | Bovines/Cattle | Bovines/Cattle MGLL/MAGL recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T18664-Ag | Equine/Horse | Equine/Horse MGLL/MAGL recombinant protein | Mammalian cell | Detail |
