Explore EPHA5 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013]
| Target ID |
GM-T18474
|
| Target Name |
EPHA5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2044
|
| Gene ID |
100066188 (Equus caballus), 100337226 (Bos taurus), 100684553 (Canis lupus familiaris), 101080281 (Felis catus)
13839 (Mus musculus), 2044 (Homo sapiens), 712074 (Macaca mulatta), 79208 (Rattus norvegicus)
|
| Target Alternative Names |
Brain-specific kinase,CEK7,Cek7,EHK-1,EHK1,EK7,EPH homology kinase 1 (EHK-1),EPH-like kinase 7 (EK7,EPHA5,Ehk1,Els1,Els1.,Epha5,Ephrin type-A receptor 5,HEK7,Hek7,Rek7,TYRO4,bsk,hEK7)
|
| Uniprot Accession |
Q60629,P54756,P54757
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000000530, ENSBTAG00000009438, ENSCAFG00845006153, ENSMUSG00000029245, ENSG00000145242, ENSMMUG00000014468
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
EPHA5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2044 | Pre-made Human EPHA5/EK7/CEK7 siRNA oligo Duplex | 2044 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79208 | Pre-made Rat Epha5/Els1/EHK-1 siRNA oligo Duplex | 79208 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13839 | Pre-made Mouse Epha5/bsk/Cek7 siRNA oligo Duplex | 13839 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712074 | Pre-made Cynomolgus/Rhesus macaque EPHA5 siRNA oligo Duplex | 712074 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080281 | Pre-made Cat/Feline EPHA5 siRNA oligo Duplex | 101080281 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100684553 | Pre-made Dog/Canine EPHA5 siRNA oligo Duplex | 100684553 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100337226 | Pre-made Bovines/Cattle EPHA5 siRNA oligo Duplex | 100337226 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066188 | Pre-made Equine/Horse EPHA5 siRNA oligo Duplex | 100066188 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPHA5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T18474-Ab | Human | Anti-Human EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T18474-Ab | Rat | Anti-Rat EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T18474-Ab | Mouse | Anti-Mouse EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T18474-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T18474-Ab | Cat/Feline | Anti-Cat/Feline EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T18474-Ab | Dog/Canine | Anti-Dog/Canine EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T18474-Ab | Bovines/Cattle | Anti-Bovines/Cattle EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T18474-Ab | Equine/Horse | Anti-Equine/Horse EPHA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPHA5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T18474-Ag | Human | Human EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T18474-Ag | Rat | Rat EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T18474-Ag | Mouse | Mouse EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T18474-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T18474-Ag | Cat/Feline | Cat/Feline EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T18474-Ag | Dog/Canine | Dog/Canine EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T18474-Ag | Bovines/Cattle | Bovines/Cattle EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T18474-Ag | Equine/Horse | Equine/Horse EPHA5 VLP (virus-like particle) | HEK293 | Products Developing |
