LATS2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore LATS2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]

Target ID GM-T18390
Target Name LATS2
Gene Group ldentifer
（Target Gene ID in Homo species) 		26524
Gene ID 100050150 (Equus caballus), 101093824 (Felis catus), 26524 (Homo sapiens), 305922 (Rattus norvegicus)
477343 (Canis lupus familiaris), 50523 (Mus musculus), 508208 (Bos taurus), 699957 (Macaca mulatta)
Target Alternative Names 4932411G09Rik,KPM,Kinase phosphorylated during mitosis protein,LATS2,Large tumor suppressor homolog 2,Lats2,Serine/threonine-protein kinase LATS2,Serine/threonine-protein kinase kpm,Warts-like kinase
Uniprot Accession Q9NRM7,Q7TSJ6
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Hippo signaling pathway
Gene Ensembl ENSECAG00000009862, ENSG00000150457, ENSCAFG00845021300, ENSMUSG00000021959,ENSMUSG00000114942, ENSBTAG00000014406, ENSMMUG00000019006
Target Classification Kinase, Tumor-associated antigen (TAA)


Pre-made viral vector of LATS2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMAD000587Human LATS2/KPM Adenovirus plasmidNM_014572.326524HumanAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMLP-SPh-020Human LATS2/KPM Lentivirus plasmidNM_01457226524HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-160Human LATS2/KPM Adenovirus plasmidNM_01457226524HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD000587Human LATS2/KPM Adenovirus particleNM_014572.326524HumanAdenovirus particleNull3xflag (C-Terminal)CMVDetail
vGMLP-SPh-020Human LATS2/KPM Lentivirus particleNM_01457226524HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPh-160Human LATS2/KPM Adenovirus particleNM_01457226524HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLP-SPm-017Mouse Lats2/4932411G09Rik/AV277261 Lentivirus plasmidNM_01577150523MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPm-144Mouse Lats2/4932411G09Rik/AV277261 Adenovirus plasmidNM_01577150523MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC004801Mouse Lats2/4932411G09Rik Mammalian (Non-Viral Vector) plasmidNM_01577150523MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP-SPm-017Mouse Lats2/4932411G09Rik/AV277261 Lentivirus particleNM_01577150523MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAP-SPm-144Mouse Lats2/4932411G09Rik/AV277261 Adenovirus particleNM_01577150523MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail


LATS2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo26524Pre-made Human LATS2/KPM siRNA oligo Duplex26524HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo305922Pre-made Rat Lats2 siRNA oligo Duplex305922RatIn-vitro grade; in-vivo gradeDetail
pGMoligo50523Pre-made Mouse Lats2/4932411G09Rik siRNA oligo Duplex50523MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo699957Pre-made Cynomolgus/Rhesus macaque LATS2 siRNA oligo Duplex699957Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101093824Pre-made Cat/Feline LATS2 siRNA oligo Duplex101093824Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo477343Pre-made Dog/Canine LATS2 siRNA oligo Duplex477343Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo508208Pre-made Bovines/Cattle LATS2 siRNA oligo Duplex508208Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100050150Pre-made Equine/Horse LATS2 siRNA oligo Duplex100050150Equine/HorseIn-vitro grade; in-vivo gradeDetail


LATS2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T18390-AbHumanAnti-Human LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T18390-AbRatAnti-Rat LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T18390-AbMouseAnti-Mouse LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T18390-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T18390-AbCat/FelineAnti-Cat/Feline LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T18390-AbDog/CanineAnti-Dog/Canine LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T18390-AbBovines/CattleAnti-Bovines/Cattle LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T18390-AbEquine/HorseAnti-Equine/Horse LATS2 monoclonal antibodymabTherapeutics Target antibodyDetail


LATS2 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T18390-AgHumanHuman LATS2 recombinant proteinMammalian cellDetail
GM-Tg-rg-T18390-AgRatRat LATS2 recombinant proteinMammalian cellDetail
GM-Tg-mg-T18390-AgMouseMouse LATS2 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T18390-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque LATS2 recombinant proteinMammalian cellDetail
GM-Tg-felg-T18390-AgCat/FelineCat/Feline LATS2 recombinant proteinMammalian cellDetail
GM-Tg-cang-T18390-AgDog/CanineDog/Canine LATS2 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T18390-AgBovines/CattleBovines/Cattle LATS2 recombinant proteinMammalian cellDetail
GM-Tg-equg-T18390-AgEquine/HorseEquine/Horse LATS2 recombinant proteinMammalian cellDetail