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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T17980
|
| Target Name |
FYN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2534
|
| Gene ID |
101085720 (Felis catus), 102149085 (Equus caballus), 14360 (Mus musculus), 25150 (Rattus norvegicus)
2534 (Homo sapiens), 475032 (Canis lupus familiaris), 527263 (Bos taurus), 574214 (Macaca mulatta)
|
| Target Alternative Names |
FYN,Fyn,SLK,SYN,p59-FYN
|
| Uniprot Accession |
P39688,Q62844,P06241,A0JNB0
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Lung Cancer
|
| Disease from KEGG |
Sphingolipid signaling pathway, Phospholipase D signaling pathway, Axon guidance, Osteoclast differentiation, Focal adhesion, Adherens junction, Platelet activation, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, Fc epsilon RI signaling pathway, Cholinergic synapse, Pathogenic Escherichia coli infection, Viral myocarditis
|
| Gene Ensembl |
ENSECAG00000008319, ENSMUSG00000019843, ENSG00000010810, ENSCAFG00845017640, ENSBTAG00000011851, ENSMMUG00000017017
|
| Target Classification |
Kinase
|
Pre-made viral vector of FYN cDNA Clones/ORF Plasmid
FYN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2534 | Pre-made Human FYN/SLK/SYN siRNA oligo Duplex | 2534 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25150 | Pre-made Rat Fyn siRNA oligo Duplex | 25150 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14360 | Pre-made Mouse Fyn siRNA oligo Duplex | 14360 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574214 | Pre-made Cynomolgus/Rhesus macaque FYN siRNA oligo Duplex | 574214 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085720 | Pre-made Cat/Feline FYN siRNA oligo Duplex | 101085720 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475032 | Pre-made Dog/Canine FYN siRNA oligo Duplex | 475032 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527263 | Pre-made Bovines/Cattle FYN siRNA oligo Duplex | 527263 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149085 | Pre-made Equine/Horse FYN siRNA oligo Duplex | 102149085 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FYN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T17980-Ab | Human | Anti-Human FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T17980-Ab | Rat | Anti-Rat FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T17980-Ab | Mouse | Anti-Mouse FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T17980-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T17980-Ab | Cat/Feline | Anti-Cat/Feline FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T17980-Ab | Dog/Canine | Anti-Dog/Canine FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T17980-Ab | Bovines/Cattle | Anti-Bovines/Cattle FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T17980-Ab | Equine/Horse | Anti-Equine/Horse FYN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FYN VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T17980-Ag | Human | Human FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T17980-Ag | Rat | Rat FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T17980-Ag | Mouse | Mouse FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T17980-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T17980-Ag | Cat/Feline | Cat/Feline FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T17980-Ag | Dog/Canine | Dog/Canine FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T17980-Ag | Bovines/Cattle | Bovines/Cattle FYN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T17980-Ag | Equine/Horse | Equine/Horse FYN VLP (virus-like particle) | HEK293 | Products Developing |
