uPA/Urokinase/PLAU Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore uPA/Urokinase/PLAU gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Pre-made viral vector of uPA/Urokinase/PLAU cDNA Clones/ORF Plasmid

uPA/Urokinase/PLAU siRNA/miRNA/oligo for RNA interfence (RNAi)

uPA/Urokinase/PLAU antibody/GMab

uPA/Urokinase/PLAU VLP (virus-like particle)/protein