Explore GIRK2/KCNJ6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
| Target ID |
GM-T17721
|
| Target Name |
GIRK2/KCNJ6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3763
|
| Gene ID |
100060665 (Equus caballus), 101080818 (Felis catus), 16522 (Mus musculus), 25743 (Rattus norvegicus)
3763 (Homo sapiens), 487756 (Canis lupus familiaris), 520743 (Bos taurus), 693675 (Macaca mulatta)
|
| Target Alternative Names |
BIR1,G protein-activated inward rectifier potassium channel 2,GIRK-2,GIRK2,Inward rectifier K(+) channel Kir3.2,KATP-2,KATP2,KCNJ6,KCNJ7,KIR3.2,KPLBS,Kcnj6,Kir3.2,Potassium channel,hiGIRK2,inwardly rectifying subfamily J member 6,weaver,wv
|
| Uniprot Accession |
P48542,P48550,P48051
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Circadian entrainment, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Oxytocin signaling pathway, GnRH secretion, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000004703, ENSMUSG00000043301, ENSG00000157542, ENSCAFG00845028925, ENSBTAG00000037616, ENSMMUG00000018136
|
Pre-made viral vector of GIRK2/KCNJ6 cDNA Clones/ORF Plasmid
GIRK2/KCNJ6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3763 | Pre-made Human KCNJ6/BIR1/GIRK2 siRNA oligo Duplex | 3763 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25743 | Pre-made Rat Kcnj6 siRNA oligo Duplex | 25743 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16522 | Pre-made Mouse Kcnj6/wv/BIR1 siRNA oligo Duplex | 16522 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693675 | Pre-made Cynomolgus/Rhesus macaque KCNJ6 siRNA oligo Duplex | 693675 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080818 | Pre-made Cat/Feline KCNJ6 siRNA oligo Duplex | 101080818 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487756 | Pre-made Dog/Canine KCNJ6 siRNA oligo Duplex | 487756 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520743 | Pre-made Bovines/Cattle KCNJ6 siRNA oligo Duplex | 520743 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060665 | Pre-made Equine/Horse KCNJ6 siRNA oligo Duplex | 100060665 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GIRK2/KCNJ6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T17721-Ab | Human | Anti-Human GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T17721-Ab | Rat | Anti-Rat GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T17721-Ab | Mouse | Anti-Mouse GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T17721-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T17721-Ab | Cat/Feline | Anti-Cat/Feline GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T17721-Ab | Dog/Canine | Anti-Dog/Canine GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T17721-Ab | Bovines/Cattle | Anti-Bovines/Cattle GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T17721-Ab | Equine/Horse | Anti-Equine/Horse GIRK2/KCNJ6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GIRK2/KCNJ6 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T17721-Ag | Human | Human GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T17721-Ag | Rat | Rat GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T17721-Ag | Mouse | Mouse GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T17721-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T17721-Ag | Cat/Feline | Cat/Feline GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T17721-Ag | Dog/Canine | Dog/Canine GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T17721-Ag | Bovines/Cattle | Bovines/Cattle GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T17721-Ag | Equine/Horse | Equine/Horse GIRK2/KCNJ6 VLP (virus-like particle) | HEK293 | Products Developing |
