Explore P2RX3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T17140
|
| Target Name |
P2RX3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5024
|
| Gene ID |
100062797 (Equus caballus), 228139 (Mus musculus), 448782 (Canis lupus familiaris), 5024 (Homo sapiens)
530468 (Bos taurus), 706503 (Macaca mulatta), 751615 (Felis catus), 81739 (Rattus norvegicus)
|
| Target Alternative Names |
4930513E20Rik,ATP receptor,P2RX3,P2X purinoceptor 3,P2X3,P2rx3,Purinergic receptor
|
| Uniprot Accession |
Q3UR32,P56373,P49654
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction
|
| Gene Ensembl |
ENSECAG00000016640, ENSMUSG00000027071, ENSCAFG00845021802, ENSG00000109991, ENSBTAG00000000376, ENSMMUG00000017813
|
Pre-made viral vector of P2RX3 cDNA Clones/ORF Plasmid
P2RX3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5024 | Pre-made Human P2RX3/P2X3 siRNA oligo Duplex | 5024 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81739 | Pre-made Rat P2rx3 siRNA oligo Duplex | 81739 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo228139 | Pre-made Mouse P2rx3/P2X3/4930513E20Rik siRNA oligo Duplex | 228139 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706503 | Pre-made Cynomolgus/Rhesus macaque P2RX3 siRNA oligo Duplex | 706503 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo751615 | Pre-made Cat/Feline P2RX3/P2X3 siRNA oligo Duplex | 751615 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo448782 | Pre-made Dog/Canine P2RX3/P2X3 siRNA oligo Duplex | 448782 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530468 | Pre-made Bovines/Cattle P2RX3 siRNA oligo Duplex | 530468 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062797 | Pre-made Equine/Horse P2RX3 siRNA oligo Duplex | 100062797 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
P2RX3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T17140-Ab | Human | Anti-Human P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T17140-Ab | Rat | Anti-Rat P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T17140-Ab | Mouse | Anti-Mouse P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T17140-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T17140-Ab | Cat/Feline | Anti-Cat/Feline P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T17140-Ab | Dog/Canine | Anti-Dog/Canine P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T17140-Ab | Bovines/Cattle | Anti-Bovines/Cattle P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T17140-Ab | Equine/Horse | Anti-Equine/Horse P2RX3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
P2RX3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T17140-Ag | Human | Human P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T17140-Ag | Rat | Rat P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T17140-Ag | Mouse | Mouse P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T17140-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T17140-Ag | Cat/Feline | Cat/Feline P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T17140-Ag | Dog/Canine | Dog/Canine P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T17140-Ag | Bovines/Cattle | Bovines/Cattle P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T17140-Ag | Equine/Horse | Equine/Horse P2RX3 VLP (virus-like particle) | HEK293 | Products Developing |
