Explore ITGAE/Integrin alpha-E/CD103 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T17122
|
| Target Name |
ITGAE/Integrin alpha-E/CD103
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3682
|
| Gene ID |
100072673 (Equus caballus), 100140050 (Bos taurus), 16407 (Mus musculus), 3682 (Homo sapiens) 480659 (Canis lupus familiaris), 493694 (Felis catus), 721483 (Macaca mulatta), 83577 (Rattus norvegicus)
|
| Target Alternative Names |
A530055J10,CD103,HML-1 antigen,HUMINAE,ITGAE,Integrin alpha-E,Integrin alpha-IEL,Itgae,Mucosal lymphocyte 1 antigen,aM290,alpha-E1,alpha-M290
|
| Uniprot Accession |
Q60677,P38570
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease from KEGG |
Regulation of actin cytoskeleton
|
| Gene Ensembl |
ENSECAG00000000897, ENSBTAG00000015258, ENSMUSG00000005947, ENSG00000083457, ENSCAFG00845016713, ENSMMUG00000008556
|
Pre-made viral vector of ITGAE/Integrin alpha-E/CD103 cDNA Clones/ORF Plasmid
ITGAE/Integrin alpha-E/CD103 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3682 | Pre-made Human ITGAE/CD103/HUMINAE siRNA oligo Duplex | 3682 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83577 | Pre-made Rat Itgae siRNA oligo Duplex | 83577 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16407 | Pre-made Mouse Itgae/CD103/aM290 siRNA oligo Duplex | 16407 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721483 | Pre-made Cynomolgus/Rhesus macaque ITGAE siRNA oligo Duplex | 721483 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493694 | Pre-made Cat/Feline ITGAE/CD103 siRNA oligo Duplex | 493694 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480659 | Pre-made Dog/Canine ITGAE siRNA oligo Duplex | 480659 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100140050 | Pre-made Bovines/Cattle ITGAE siRNA oligo Duplex | 100140050 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072673 | Pre-made Equine/Horse ITGAE siRNA oligo Duplex | 100072673 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ITGAE/Integrin alpha-E/CD103 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T17122-Ab | Human | Anti-Human ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T17122-Ab | Rat | Anti-Rat ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T17122-Ab | Mouse | Anti-Mouse ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T17122-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T17122-Ab | Cat/Feline | Anti-Cat/Feline ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T17122-Ab | Dog/Canine | Anti-Dog/Canine ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T17122-Ab | Bovines/Cattle | Anti-Bovines/Cattle ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T17122-Ab | Equine/Horse | Anti-Equine/Horse ITGAE/Integrin alpha-E/CD103 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T17122-Ag | Human | Human ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T17122-Ag | Rat | Rat ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T17122-Ag | Mouse | Mouse ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T17122-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T17122-Ag | Cat/Feline | Cat/Feline ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T17122-Ag | Dog/Canine | Dog/Canine ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T17122-Ag | Bovines/Cattle | Bovines/Cattle ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T17122-Ag | Equine/Horse | Equine/Horse ITGAE/Integrin alpha-E/CD103 VLP (virus-like particle) | HEK293 | Products Developing |