Explore CA12/CA-XII gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014]
| Target ID |
GM-T16987
|
| Target Name |
CA12/CA-XII
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
771
|
| Gene ID |
100054028 (Equus caballus), 101090522 (Felis catus), 363085 (Rattus norvegicus), 478333 (Canis lupus familiaris)
614323 (Bos taurus), 705838 (Macaca mulatta), 76459 (Mus musculus), 771 (Homo sapiens)
|
| Target Alternative Names |
2310047E01Rik,CA-XII,CA12,CAXII,Ca12,Car12,Carbonate dehydratase XII,Carbonic anhydrase 12,Carbonic anhydrase XII (CA-XII),HsT18816,T18816,Tumor antigen HOM-RCC-3.1.3
|
| Uniprot Accession |
Q8CI85,O43570
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000017217, ENSCAFG00845020844, ENSBTAG00000019390, ENSMMUG00000021338, ENSMUSG00000032373, ENSG00000074410
|
Pre-made viral vector of CA12/CA-XII cDNA Clones/ORF Plasmid
CA12/CA-XII siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo771 | Pre-made Human CA12/CAXII/CA-XII siRNA oligo Duplex | 771 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363085 | Pre-made Rat Car12/Ca12 siRNA oligo Duplex | 363085 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76459 | Pre-made Mouse Car12/Ca12/CA-XII siRNA oligo Duplex | 76459 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705838 | Pre-made Cynomolgus/Rhesus macaque CA12 siRNA oligo Duplex | 705838 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090522 | Pre-made Cat/Feline CA12 siRNA oligo Duplex | 101090522 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478333 | Pre-made Dog/Canine CA12 siRNA oligo Duplex | 478333 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614323 | Pre-made Bovines/Cattle CA12 siRNA oligo Duplex | 614323 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054028 | Pre-made Equine/Horse CA12 siRNA oligo Duplex | 100054028 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CA12/CA-XII antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16987-Ab | Human | Anti-Human CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16987-Ab | Rat | Anti-Rat CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16987-Ab | Mouse | Anti-Mouse CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16987-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16987-Ab | Cat/Feline | Anti-Cat/Feline CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16987-Ab | Dog/Canine | Anti-Dog/Canine CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16987-Ab | Bovines/Cattle | Anti-Bovines/Cattle CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16987-Ab | Equine/Horse | Anti-Equine/Horse CA12/CA-XII monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CA12/CA-XII VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16987-Ag | Human | Human CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T16987-Ag | Rat | Rat CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T16987-Ag | Mouse | Mouse CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16987-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T16987-Ag | Cat/Feline | Cat/Feline CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T16987-Ag | Dog/Canine | Dog/Canine CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T16987-Ag | Bovines/Cattle | Bovines/Cattle CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T16987-Ag | Equine/Horse | Equine/Horse CA12/CA-XII VLP (virus-like particle) | HEK293 | Products Developing |
