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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
| Target ID |
GM-T16808
|
| Target Name |
PRMT1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3276
|
| Gene ID |
100052097 (Equus caballus), 101095389 (Felis catus), 15469 (Mus musculus), 3276 (Homo sapiens) 476411 (Canis lupus familiaris), 520388 (Bos taurus), 60421 (Rattus norvegicus), 719419 (Macaca mulatta)
|
| Target Alternative Names |
6720434D09Rik,ANM1,HCP1,HRMT1L2,Histone-arginine N-methyltransferase PRMT1,Hrmt1l2,IR1B4,Interferon receptor 1-bound protein 4,Mrmt1,PRMT1,Prmt1,Protein arginine N-methyltransferase 1
|
| Uniprot Accession |
Q9JIF0,Q99873,Q63009
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
FoxO signaling pathway
|
| Gene Ensembl |
ENSECAG00000024076, ENSMUSG00000109324, ENSG00000126457, ENSCAFG00845022617, ENSBTAG00000006646, ENSMMUG00000003029
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of PRMT1 cDNA Clones/ORF Plasmid
PRMT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3276 | Pre-made Human PRMT1/ANM1/HCP1 siRNA oligo Duplex | 3276 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60421 | Pre-made Rat Prmt1/Hrmt1l2 siRNA oligo Duplex | 60421 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15469 | Pre-made Mouse Prmt1/Mrmt1/Hrmt1l2 siRNA oligo Duplex | 15469 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719419 | Pre-made Cynomolgus/Rhesus macaque PRMT1 siRNA oligo Duplex | 719419 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095389 | Pre-made Cat/Feline PRMT1 siRNA oligo Duplex | 101095389 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476411 | Pre-made Dog/Canine PRMT1 siRNA oligo Duplex | 476411 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520388 | Pre-made Bovines/Cattle PRMT1/HRMT1L2 siRNA oligo Duplex | 520388 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052097 | Pre-made Equine/Horse PRMT1 siRNA oligo Duplex | 100052097 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRMT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16808-Ab | Human | Anti-Human PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16808-Ab | Rat | Anti-Rat PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16808-Ab | Mouse | Anti-Mouse PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16808-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16808-Ab | Cat/Feline | Anti-Cat/Feline PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16808-Ab | Dog/Canine | Anti-Dog/Canine PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16808-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16808-Ab | Equine/Horse | Anti-Equine/Horse PRMT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PRMT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16808-Ag | Human | Human PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T16808-Ag | Rat | Rat PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T16808-Ag | Mouse | Mouse PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T16808-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T16808-Ag | Cat/Feline | Cat/Feline PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T16808-Ag | Dog/Canine | Dog/Canine PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T16808-Ag | Bovines/Cattle | Bovines/Cattle PRMT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T16808-Ag | Equine/Horse | Equine/Horse PRMT1 recombinant protein | Mammalian cell | Detail |