Explore ATP6V1A/v-ATPase-A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T16731
|
| Target Name |
ATP6V1A/v-ATPase-A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
523
|
| Gene ID |
100061223 (Equus caballus), 101091723 (Felis catus), 11964 (Mus musculus), 282147 (Bos taurus) 487981 (Canis lupus familiaris), 523 (Homo sapiens), 685232 (Rattus norvegicus), 709958 (Macaca mulatta)
|
| Target Alternative Names |
ARCL2D,ATP6A1,ATP6V1A,ATP6V1A1,Atp6a1,Atp6a2,Atp6v1a,Atp6v1a1,DEE93,HO68,IECEE3,V-ATPase 69 kDa subunit,V-ATPase subunit A,V-type proton ATPase catalytic subunit A,VA68,VPP2,Vacuolar ATPase isoform VA68,Vacuolar proton pump subunit alpha,Vma1,v-ATPase-A
|
| Uniprot Accession |
P50516,P31404,P38606
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Phagosome, Epithelial cell signaling in Helicobacter pylori infection, Human papillomavirus infection, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000021773, ENSMUSG00000052459, ENSBTAG00000002703, ENSCAFG00845030309, ENSG00000114573, ENSMMUG00000020740
|
Pre-made viral vector of ATP6V1A/v-ATPase-A cDNA Clones/ORF Plasmid
ATP6V1A/v-ATPase-A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo523 | Pre-made Human ATP6V1A/HO68/VA68 siRNA oligo Duplex | 523 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo685232 | Pre-made Rat Atp6v1a/Atp6v1a1 siRNA oligo Duplex | 685232 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11964 | Pre-made Mouse Atp6v1a/VA68/VPP2 siRNA oligo Duplex | 11964 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709958 | Pre-made Cynomolgus/Rhesus macaque ATP6V1A siRNA oligo Duplex | 709958 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091723 | Pre-made Cat/Feline ATP6V1A siRNA oligo Duplex | 101091723 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487981 | Pre-made Dog/Canine ATP6V1A siRNA oligo Duplex | 487981 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282147 | Pre-made Bovines/Cattle ATP6V1A/ATP6A1 siRNA oligo Duplex | 282147 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061223 | Pre-made Equine/Horse ATP6V1A siRNA oligo Duplex | 100061223 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ATP6V1A/v-ATPase-A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16731-Ab | Human | Anti-Human ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16731-Ab | Rat | Anti-Rat ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16731-Ab | Mouse | Anti-Mouse ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16731-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16731-Ab | Cat/Feline | Anti-Cat/Feline ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16731-Ab | Dog/Canine | Anti-Dog/Canine ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16731-Ab | Bovines/Cattle | Anti-Bovines/Cattle ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16731-Ab | Equine/Horse | Anti-Equine/Horse ATP6V1A/v-ATPase-A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ATP6V1A/v-ATPase-A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16731-Ag | Human | Human ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T16731-Ag | Rat | Rat ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T16731-Ag | Mouse | Mouse ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T16731-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T16731-Ag | Cat/Feline | Cat/Feline ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T16731-Ag | Dog/Canine | Dog/Canine ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T16731-Ag | Bovines/Cattle | Bovines/Cattle ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T16731-Ag | Equine/Horse | Equine/Horse ATP6V1A/v-ATPase-A recombinant protein | Mammalian cell | Detail |