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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]
| Target ID |
GM-T16633
|
| Target Name |
SSTR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6751
|
| Gene ID |
100060276 (Equus caballus), 101093025 (Felis catus), 107131319 (Bos taurus), 20605 (Mus musculus) 25033 (Rattus norvegicus), 403455 (Canis lupus familiaris), 6751 (Homo sapiens), 698123 (Macaca mulatta)
|
| Target Alternative Names |
Gpcrrna,SRIF-2,SS-1-R,SS1-R,SS1R,SST1,SSTR1,Smstr-1,Smstr1,Somatostatin receptor type 1,Sstr1,sst1
|
| Uniprot Accession |
P30873,P28646,Q49LX5,P30872
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000004716, ENSMUSG00000035431, ENSCAFG00845003155, ENSG00000139874, ENSMMUG00000039337
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
SSTR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6751 | Pre-made Human SSTR1/SS1R/SST1 siRNA oligo Duplex | 6751 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25033 | Pre-made Rat Sstr1/Gpcrrna siRNA oligo Duplex | 25033 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20605 | Pre-made Mouse Sstr1/SS1R/sst1 siRNA oligo Duplex | 20605 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698123 | Pre-made Cynomolgus/Rhesus macaque SSTR1 siRNA oligo Duplex | 698123 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093025 | Pre-made Cat/Feline SSTR1 siRNA oligo Duplex | 101093025 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403455 | Pre-made Dog/Canine SSTR1 siRNA oligo Duplex | 403455 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107131319 | Pre-made Bovines/Cattle SSTR1 siRNA oligo Duplex | 107131319 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060276 | Pre-made Equine/Horse SSTR1 siRNA oligo Duplex | 100060276 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SSTR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16633-Ab | Human | Anti-Human SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16633-Ab | Rat | Anti-Rat SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16633-Ab | Mouse | Anti-Mouse SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16633-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16633-Ab | Cat/Feline | Anti-Cat/Feline SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16633-Ab | Dog/Canine | Anti-Dog/Canine SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16633-Ab | Bovines/Cattle | Anti-Bovines/Cattle SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16633-Ab | Equine/Horse | Anti-Equine/Horse SSTR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SSTR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16633-Ag | Human | Human SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T16633-Ag | Rat | Rat SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T16633-Ag | Mouse | Mouse SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16633-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T16633-Ag | Cat/Feline | Cat/Feline SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T16633-Ag | Dog/Canine | Dog/Canine SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T16633-Ag | Bovines/Cattle | Bovines/Cattle SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T16633-Ag | Equine/Horse | Equine/Horse SSTR1 VLP (virus-like particle) | HEK293 | Products Developing |