Explore CEA/CD66e/CEACAM5 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
| Target ID |
GM-T16601
|
| Target Name |
CEA/CD66e/CEACAM5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1048
|
| Gene ID |
1048 (Homo sapiens), 705689 (Macaca mulatta)
|
| Target Alternative Names |
CD66e,CEA,CEACAM5,Carcinoembryonic antigen (CEA),Carcinoembryonic antigen-related cell adhesion molecule 5 (CEA cell adhesion molecule 5),Cell adhesion molecule CEACAM5,Meconium antigen 100
|
| Uniprot Accession |
P06731
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer, Prostate Cancer
|
| Gene Ensembl |
ENSG00000105388, ENSMMUG00000018103
|
Pre-made viral vector of CEA/CD66e/CEACAM5 cDNA Clones/ORF Plasmid
CEA/CD66e/CEACAM5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1048 | Pre-made Human CEACAM5/CEA/CD66e siRNA oligo Duplex | 1048 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705689 | Pre-made Cynomolgus/Rhesus macaque CEACAM5/CEA siRNA oligo Duplex | 705689 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CEA/CD66e/CEACAM5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16601-Ab | Human | Anti-Human CEA/CD66e/CEACAM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16601-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CEA/CD66e/CEACAM5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CEA/CD66e/CEACAM5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16601-Ag | Human | Human CEA/CD66e/CEACAM5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16601-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CEA/CD66e/CEACAM5 VLP (virus-like particle) | HEK293 | Products Developing |
