Explore FASN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T16514
|
| Target Name |
FASN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2194
|
| Gene ID |
100057311 (Equus caballus), 100270775 (Felis catus), 14104 (Mus musculus), 2194 (Homo sapiens)
281152 (Bos taurus), 483378 (Canis lupus familiaris), 50671 (Rattus norvegicus), 715708 (Macaca mulatta)
|
| Target Alternative Names |
A630082H08Rik,FAS,FASN,Fasn,Fatty acid synthase,OA-519,SDR27X1,Type I fatty acid synthase
|
| Uniprot Accession |
P19096,P49327,Q71SP7,P12785
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000019125,ENSECAG00000044247, ENSMUSG00000025153, ENSG00000169710, ENSBTAG00000015980, ENSCAFG00845007524, ENSMMUG00000012811
|
| Target Classification |
Tumor-associated antigen (TAA)
|
FASN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2194 | Pre-made Human FASN/FAS/OA-519 siRNA oligo Duplex | 2194 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50671 | Pre-made Rat Fasn siRNA oligo Duplex | 50671 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14104 | Pre-made Mouse Fasn/FAS/A630082H08Rik siRNA oligo Duplex | 14104 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715708 | Pre-made Cynomolgus/Rhesus macaque FASN siRNA oligo Duplex | 715708 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100270775 | Pre-made Cat/Feline FASN siRNA oligo Duplex | 100270775 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483378 | Pre-made Dog/Canine FASN siRNA oligo Duplex | 483378 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281152 | Pre-made Bovines/Cattle FASN siRNA oligo Duplex | 281152 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057311 | Pre-made Equine/Horse FASN siRNA oligo Duplex | 100057311 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FASN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16514-Ab | Human | Anti-Human FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16514-Ab | Rat | Anti-Rat FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16514-Ab | Mouse | Anti-Mouse FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16514-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16514-Ab | Cat/Feline | Anti-Cat/Feline FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16514-Ab | Dog/Canine | Anti-Dog/Canine FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16514-Ab | Bovines/Cattle | Anti-Bovines/Cattle FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16514-Ab | Equine/Horse | Anti-Equine/Horse FASN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FASN VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16514-Ag | Human | Human FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T16514-Ag | Rat | Rat FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T16514-Ag | Mouse | Mouse FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16514-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T16514-Ag | Cat/Feline | Cat/Feline FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T16514-Ag | Dog/Canine | Dog/Canine FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T16514-Ag | Bovines/Cattle | Bovines/Cattle FASN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T16514-Ag | Equine/Horse | Equine/Horse FASN VLP (virus-like particle) | HEK293 | Products Developing |
