Explore Connexin-50/GJA8/Cx50 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]
| Target ID |
GM-T16353
|
| Target Name |
Connexin-50/GJA8/Cx50
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2703
|
| Gene ID |
100065084 (Equus caballus), 101096160 (Felis catus), 14616 (Mus musculus), 2703 (Homo sapiens)
29601 (Rattus norvegicus), 483156 (Canis lupus familiaris), 524042 (Bos taurus), 701415 (Macaca mulatta)
|
| Target Alternative Names |
GJA8,Gja8,CXNL,dcm,Aey5,Cx50,Cxnl,Cnx50,Lop10,CAE,CAE1,CX50,CZP1,MP70,CTRCT1
|
| Uniprot Accession |
P28236,P48165,Q8K4Q9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000002537, ENSMUSG00000049908, ENSG00000121634, ENSCAFG00845010011, ENSBTAG00000021833, ENSMMUG00000001382
|
| Target Classification |
|
Pre-made viral vector of Connexin-50/GJA8/Cx50 cDNA Clones/ORF Plasmid
Connexin-50/GJA8/Cx50 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2703 | Pre-made Human GJA8/CAE/CAE1 siRNA oligo Duplex | 2703 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29601 | Pre-made Rat Gja8/Cx50/Cxnl siRNA oligo Duplex | 29601 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14616 | Pre-made Mouse Gja8/dcm/Aey5 siRNA oligo Duplex | 14616 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701415 | Pre-made Cynomolgus/Rhesus macaque GJA8/CXNL siRNA oligo Duplex | 701415 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096160 | Pre-made Cat/Feline GJA8 siRNA oligo Duplex | 101096160 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483156 | Pre-made Dog/Canine GJA8 siRNA oligo Duplex | 483156 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524042 | Pre-made Bovines/Cattle GJA8/CXNL siRNA oligo Duplex | 524042 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065084 | Pre-made Equine/Horse GJA8/CXNL siRNA oligo Duplex | 100065084 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Connexin-50/GJA8/Cx50 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T16353-Ab | Human | Anti-Human Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T16353-Ab | Rat | Anti-Rat Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T16353-Ab | Mouse | Anti-Mouse Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T16353-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T16353-Ab | Cat/Feline | Anti-Cat/Feline Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T16353-Ab | Dog/Canine | Anti-Dog/Canine Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T16353-Ab | Bovines/Cattle | Anti-Bovines/Cattle Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T16353-Ab | Equine/Horse | Anti-Equine/Horse Connexin-50/GJA8/Cx50 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Connexin-50/GJA8/Cx50 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T16353-Ag | Human | Human Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T16353-Ag | Rat | Rat Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T16353-Ag | Mouse | Mouse Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T16353-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T16353-Ag | Cat/Feline | Cat/Feline Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T16353-Ag | Dog/Canine | Dog/Canine Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T16353-Ag | Bovines/Cattle | Bovines/Cattle Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T16353-Ag | Equine/Horse | Equine/Horse Connexin-50/GJA8/Cx50 VLP (virus-like particle) | HEK293 | Products Developing |
