Explore HNF4A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
| Target ID |
GM-T15514
|
| Target Name |
HNF4A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3172
|
| Gene ID |
100056007 (Equus caballus), 101092841 (Felis catus), 15378 (Mus musculus), 25735 (Rattus norvegicus) 3172 (Homo sapiens), 485884 (Canis lupus familiaris), 509200 (Bos taurus), 717972 (Macaca mulatta)
|
| Target Alternative Names |
FRTS4,HNF-4,HNF-4-alpha,HNF4,HNF4A,HNF4a7,HNF4a8,HNF4a9,HNF4alpha,Hepatocyte nuclear factor 4-alpha,Hnf4,Hnf4a,Hnf4alpha,MODY,MODY1,NR2A1,NR2A21,Nr2a1,Nuclear receptor subfamily 2 group A member 1,TCF,TCF-14,TCF14,Tcf14,Transcription factor 14 (TCF-14),Transcription factor HNF-4
|
| Uniprot Accession |
P49698,P22449,P41235
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024450, ENSMUSG00000017950, ENSG00000101076, ENSCAFG00845013683, ENSBTAG00000012116, ENSMMUG00000006464
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HNF4A cDNA Clones/ORF Plasmid
HNF4A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3172 | Pre-made Human HNF4A/TCF/HNF4 siRNA oligo Duplex | 3172 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25735 | Pre-made Rat Hnf4a/Hnf4/Hnf4alpha siRNA oligo Duplex | 25735 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15378 | Pre-made Mouse Hnf4a/Hnf4/HNF-4 siRNA oligo Duplex | 15378 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717972 | Pre-made Cynomolgus/Rhesus macaque HNF4A siRNA oligo Duplex | 717972 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092841 | Pre-made Cat/Feline HNF4A siRNA oligo Duplex | 101092841 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485884 | Pre-made Dog/Canine HNF4A siRNA oligo Duplex | 485884 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509200 | Pre-made Bovines/Cattle HNF4A siRNA oligo Duplex | 509200 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056007 | Pre-made Equine/Horse HNF4A siRNA oligo Duplex | 100056007 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HNF4A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15514-Ab | Human | Anti-Human HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15514-Ab | Rat | Anti-Rat HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15514-Ab | Mouse | Anti-Mouse HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15514-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15514-Ab | Cat/Feline | Anti-Cat/Feline HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15514-Ab | Dog/Canine | Anti-Dog/Canine HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15514-Ab | Bovines/Cattle | Anti-Bovines/Cattle HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15514-Ab | Equine/Horse | Anti-Equine/Horse HNF4A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HNF4A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15514-Ag | Human | Human HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T15514-Ag | Rat | Rat HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T15514-Ag | Mouse | Mouse HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T15514-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T15514-Ag | Cat/Feline | Cat/Feline HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T15514-Ag | Dog/Canine | Dog/Canine HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T15514-Ag | Bovines/Cattle | Bovines/Cattle HNF4A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T15514-Ag | Equine/Horse | Equine/Horse HNF4A recombinant protein | Mammalian cell | Detail |