Explore IRS1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
| Target ID |
GM-T15510
|
| Target Name |
IRS1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3667
|
| Gene ID |
100061987 (Equus caballus), 101087257 (Felis catus), 16367 (Mus musculus), 25467 (Rattus norvegicus)
3667 (Homo sapiens), 486148 (Canis lupus familiaris), 538598 (Bos taurus), 707870 (Macaca mulatta)
|
| Target Alternative Names |
G972R,HIRS-1,IRS-1,IRS1,IRS1IRM,Insulin receptor substrate 1,Irs1
|
| Uniprot Accession |
P35569,P35570,P35568
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
cGMP-PKG signaling pathway, FoxO signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Neurotrophin signaling pathway, Adipocytokine signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000007393, ENSMUSG00000055980, ENSG00000169047, ENSBTAG00000021308, ENSMMUG00000019467
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IRS1 cDNA Clones/ORF Plasmid
IRS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3667 | Pre-made Human IRS1/HIRS-1 siRNA oligo Duplex | 3667 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25467 | Pre-made Rat Irs1/IRS1IRM siRNA oligo Duplex | 25467 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16367 | Pre-made Mouse Irs1/G972R/IRS-1 siRNA oligo Duplex | 16367 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707870 | Pre-made Cynomolgus/Rhesus macaque IRS1 siRNA oligo Duplex | 707870 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087257 | Pre-made Cat/Feline IRS1 siRNA oligo Duplex | 101087257 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486148 | Pre-made Dog/Canine IRS1 siRNA oligo Duplex | 486148 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538598 | Pre-made Bovines/Cattle IRS1 siRNA oligo Duplex | 538598 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061987 | Pre-made Equine/Horse IRS1 siRNA oligo Duplex | 100061987 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IRS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15510-Ab | Human | Anti-Human IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15510-Ab | Rat | Anti-Rat IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15510-Ab | Mouse | Anti-Mouse IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15510-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15510-Ab | Cat/Feline | Anti-Cat/Feline IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15510-Ab | Dog/Canine | Anti-Dog/Canine IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15510-Ab | Bovines/Cattle | Anti-Bovines/Cattle IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15510-Ab | Equine/Horse | Anti-Equine/Horse IRS1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
IRS1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15510-Ag | Human | Human IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15510-Ag | Rat | Rat IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15510-Ag | Mouse | Mouse IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15510-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15510-Ag | Cat/Feline | Cat/Feline IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15510-Ag | Dog/Canine | Dog/Canine IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15510-Ag | Bovines/Cattle | Bovines/Cattle IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15510-Ag | Equine/Horse | Equine/Horse IRS1 VLP (virus-like particle) | HEK293 | Products Developing |
