Explore F11R/CD321 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T15438
|
| Target Name |
F11R/CD321
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
50848
|
| Gene ID |
100066720 (Equus caballus), 116479 (Rattus norvegicus), 16456 (Mus musculus), 281258 (Bos taurus)
478974 (Canis lupus familiaris), 50848 (Homo sapiens), 653015 (Felis catus), 719824 (Macaca mulatta)
|
| Target Alternative Names |
9130004G24,CD321,ESTM33,F11R,F11r,JAM,JAM-1,JAM-A,JAM1,JAMA,JCAM,Jam1,Jcam,Jcam1,Junctional adhesion molecule 1 (JAM-1),Junctional adhesion molecule A,KAT,Ly106,PAM-1,Platelet F11 receptor,Platelet adhesion molecule 1 (PAM-1)
|
| Uniprot Accession |
Q9JHY1,O88792,Q9XT56,Q9Y624,Q2WGK2
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Epithelial cell signaling in Helicobacter pylori infection
|
| Gene Ensembl |
ENSECAG00000018579, ENSMUSG00000038235, ENSBTAG00000017846, ENSCAFG00845030092, ENSG00000158769, ENSMMUG00000001996
|
Pre-made viral vector of F11R/CD321 cDNA Clones/ORF Plasmid
F11R/CD321 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo50848 | Pre-made Human F11R/JAM/KAT siRNA oligo Duplex | 50848 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116479 | Pre-made Rat F11r/Jam1 siRNA oligo Duplex | 116479 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16456 | Pre-made Mouse F11r/JAM/Jcam siRNA oligo Duplex | 16456 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719824 | Pre-made Cynomolgus/Rhesus macaque F11R siRNA oligo Duplex | 719824 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo653015 | Pre-made Cat/Feline F11R/JAM1/JAM-1 siRNA oligo Duplex | 653015 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478974 | Pre-made Dog/Canine F11R/JAM-A siRNA oligo Duplex | 478974 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281258 | Pre-made Bovines/Cattle F11R/JAM1 siRNA oligo Duplex | 281258 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066720 | Pre-made Equine/Horse F11R siRNA oligo Duplex | 100066720 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
F11R/CD321 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15438-Ab | Human | Anti-Human F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15438-Ab | Rat | Anti-Rat F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15438-Ab | Mouse | Anti-Mouse F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15438-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15438-Ab | Cat/Feline | Anti-Cat/Feline F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15438-Ab | Dog/Canine | Anti-Dog/Canine F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15438-Ab | Bovines/Cattle | Anti-Bovines/Cattle F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15438-Ab | Equine/Horse | Anti-Equine/Horse F11R/CD321 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
F11R/CD321 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15438-Ag | Human | Human F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15438-Ag | Rat | Rat F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15438-Ag | Mouse | Mouse F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15438-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15438-Ag | Cat/Feline | Cat/Feline F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15438-Ag | Dog/Canine | Dog/Canine F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15438-Ag | Bovines/Cattle | Bovines/Cattle F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15438-Ag | Equine/Horse | Equine/Horse F11R/CD321 VLP (virus-like particle) | HEK293 | Products Developing |
