Explore CX3CR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
| Target ID |
GM-T15033
|
| Target Name |
CX3CR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1524
|
| Gene ID |
100068350 (Equus caballus), 100124525 (Bos taurus), 101099898 (Felis catus), 13051 (Mus musculus)
1524 (Homo sapiens), 171056 (Rattus norvegicus), 485599 (Canis lupus familiaris), 693926 (Macaca mulatta)
|
| Target Alternative Names |
Beta chemokine receptor-like 1 (CMK-BRL-1,C-X3-C CKR-1,CCRL1,CMK-BRL1),CMKBRL1,CMKDR1,CX3C chemokine receptor 1,CX3CR1,Cx3cr1,Fractalkine receptor,G-protein coupled receptor 13,GPR13,GPRV28,Rbs11,V28,mCX3CR1
|
| Uniprot Accession |
A6QNL7,Q9Z0D9,P49238,P35411
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000004442, ENSBTAG00000002923, ENSMUSG00000052336, ENSG00000168329, ENSCAFG00845015921, ENSMMUG00000065286
|
| Target Classification |
GPCR, Checkpoint-Immuno Oncology
|
Pre-made viral vector of CX3CR1 cDNA Clones/ORF Plasmid
CX3CR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1524 | Pre-made Human CX3CR1/V28/CCRL1 siRNA oligo Duplex | 1524 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171056 | Pre-made Rat Cx3cr1/Rbs11 siRNA oligo Duplex | 171056 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13051 | Pre-made Mouse Cx3cr1/mCX3CR1 siRNA oligo Duplex | 13051 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693926 | Pre-made Cynomolgus/Rhesus macaque CX3CR1 siRNA oligo Duplex | 693926 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099898 | Pre-made Cat/Feline CX3CR1 siRNA oligo Duplex | 101099898 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485599 | Pre-made Dog/Canine CX3CR1 siRNA oligo Duplex | 485599 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100124525 | Pre-made Bovines/Cattle CX3CR1 siRNA oligo Duplex | 100124525 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068350 | Pre-made Equine/Horse CX3CR1 siRNA oligo Duplex | 100068350 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CX3CR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15033-Ab | Human | Anti-Human CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T15033-Ab | Rat | Anti-Rat CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T15033-Ab | Mouse | Anti-Mouse CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T15033-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T15033-Ab | Cat/Feline | Anti-Cat/Feline CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T15033-Ab | Dog/Canine | Anti-Dog/Canine CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T15033-Ab | Bovines/Cattle | Anti-Bovines/Cattle CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T15033-Ab | Equine/Horse | Anti-Equine/Horse CX3CR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CX3CR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15033-Ag | Human | Human CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15033-Ag | Rat | Rat CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15033-Ag | Mouse | Mouse CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15033-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15033-Ag | Cat/Feline | Cat/Feline CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15033-Ag | Dog/Canine | Dog/Canine CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15033-Ag | Bovines/Cattle | Bovines/Cattle CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15033-Ag | Equine/Horse | Equine/Horse CX3CR1 VLP (virus-like particle) | HEK293 | Products Developing |
