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Target
sublocation: Introcelluar Protein.
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T14181
|
| Target Name |
TERF2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7014
|
| Gene ID |
100067122 (Equus caballus), 101083387 (Felis catus), 21750 (Mus musculus), 361403 (Rattus norvegicus) 489736 (Canis lupus familiaris), 506501 (Bos taurus), 7014 (Homo sapiens), 704879 (Macaca mulatta)
|
| Target Alternative Names |
TERF2,TRBF2,TRF2,TTAGGG repeat-binding factor 2,Telomeric DNA-binding protein,Telomeric repeat-binding factor 2,Terf2,Trf2
|
| Uniprot Accession |
O35144,Q15554
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024534, ENSMUSG00000031921, ENSCAFG00845009607, ENSBTAG00000007617, ENSG00000132604, ENSMMUG00000016633
|
| Target Classification |
Tumor-associated antigen (TAA)
|
TERF2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7014 | Pre-made Human TERF2/TRF2/TRBF2 siRNA oligo Duplex | 7014 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361403 | Pre-made Rat Terf2/Trf2 siRNA oligo Duplex | 361403 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21750 | Pre-made Mouse Terf2/TRF2 siRNA oligo Duplex | 21750 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704879 | Pre-made Cynomolgus/Rhesus macaque TERF2 siRNA oligo Duplex | 704879 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083387 | Pre-made Cat/Feline TERF2 siRNA oligo Duplex | 101083387 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489736 | Pre-made Dog/Canine TERF2 siRNA oligo Duplex | 489736 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506501 | Pre-made Bovines/Cattle TERF2 siRNA oligo Duplex | 506501 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067122 | Pre-made Equine/Horse TERF2 siRNA oligo Duplex | 100067122 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TERF2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T14181-Ab | Human | Anti-Human TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T14181-Ab | Rat | Anti-Rat TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T14181-Ab | Mouse | Anti-Mouse TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T14181-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T14181-Ab | Cat/Feline | Anti-Cat/Feline TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T14181-Ab | Dog/Canine | Anti-Dog/Canine TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T14181-Ab | Bovines/Cattle | Anti-Bovines/Cattle TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T14181-Ab | Equine/Horse | Anti-Equine/Horse TERF2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TERF2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T14181-Ag | Human | Human TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T14181-Ag | Rat | Rat TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T14181-Ag | Mouse | Mouse TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T14181-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T14181-Ag | Cat/Feline | Cat/Feline TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T14181-Ag | Dog/Canine | Dog/Canine TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T14181-Ag | Bovines/Cattle | Bovines/Cattle TERF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T14181-Ag | Equine/Horse | Equine/Horse TERF2 recombinant protein | Mammalian cell | Detail |