Explore KLB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Enables fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway. Predicted to act upstream of or within positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Predicted to be located in plasma membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T14110
|
| Target Name |
KLB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
152831
|
| Gene ID |
100064228 (Equus caballus), 101083930 (Felis catus), 152831 (Homo sapiens), 289625 (Rattus norvegicus)
479110 (Canis lupus familiaris), 514925 (Bos taurus), 699115 (Macaca mulatta), 83379 (Mus musculus)
|
| Target Alternative Names |
KLB,Klb,BKL,Klb-ps1,RGD1308227,AABR07015003.1,betaKlotho
|
| Uniprot Accession |
Q86Z14,Q99N32
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000022879, ENSG00000134962, ENSCAFG00845004657, ENSBTAG00000014517, ENSMMUG00000008834, ENSMUSG00000029195
|
| Target Classification |
|
KLB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo152831 | Pre-made Human KLB/BKL siRNA oligo Duplex | 152831 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289625 | Pre-made Rat Klb/Klb-ps1/RGD1308227 siRNA oligo Duplex | 289625 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83379 | Pre-made Mouse Klb/betaKlotho siRNA oligo Duplex | 83379 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699115 | Pre-made Cynomolgus/Rhesus macaque KLB siRNA oligo Duplex | 699115 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083930 | Pre-made Cat/Feline KLB siRNA oligo Duplex | 101083930 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479110 | Pre-made Dog/Canine KLB siRNA oligo Duplex | 479110 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514925 | Pre-made Bovines/Cattle KLB siRNA oligo Duplex | 514925 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064228 | Pre-made Equine/Horse KLB siRNA oligo Duplex | 100064228 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KLB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T14110-Ab | Human | Anti-Human KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T14110-Ab | Rat | Anti-Rat KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T14110-Ab | Mouse | Anti-Mouse KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T14110-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T14110-Ab | Cat/Feline | Anti-Cat/Feline KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T14110-Ab | Dog/Canine | Anti-Dog/Canine KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T14110-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T14110-Ab | Equine/Horse | Anti-Equine/Horse KLB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
KLB VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T14110-Ag | Human | Human KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T14110-Ag | Rat | Rat KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T14110-Ag | Mouse | Mouse KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T14110-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T14110-Ag | Cat/Feline | Cat/Feline KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T14110-Ag | Dog/Canine | Dog/Canine KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T14110-Ag | Bovines/Cattle | Bovines/Cattle KLB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T14110-Ag | Equine/Horse | Equine/Horse KLB VLP (virus-like particle) | HEK293 | Products Developing |
