Integrin Beta 7/ITGB7 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Integrin Beta 7/ITGB7 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

Target ID GM-T14065
Target Name Integrin Beta 7/ITGB7
Gene Group ldentifer
(Target Gene ID in Homo species)
3695
Gene ID 100063747 (Equus caballus), 101099982 (Felis catus), 16421 (Mus musculus), 25713 (Rattus norvegicus)
3695 (Homo sapiens), 477598 (Canis lupus familiaris), 514031 (Bos taurus), 699405 (Macaca mulatta)
Target Alternative Names Gut homing receptor beta subunit,ITGB7,Integrin Beta 7,Integrin beta-7,Itgb7,Ly69
Uniprot Accession P26011,P26010
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target, INN Index
Disease from KEGG PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Cell adhesion molecules, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
Gene Ensembl ENSECAG00000013502, ENSMUSG00000001281, ENSG00000139626, ENSCAFG00845021413, ENSBTAG00000018993, ENSMMUG00000005245
Target Classification Checkpoint-Immuno Oncology


Pre-made viral vector of Integrin Beta 7/ITGB7 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV000442Human ITGB7 Lentivirus plasmidNM_000889.23695HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000442Human ITGB7 Lentivirus particleNM_000889.23695HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Integrin Beta 7/ITGB7 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3695Pre-made Human ITGB7 siRNA oligo Duplex3695HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25713Pre-made Rat Itgb7 siRNA oligo Duplex25713RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16421Pre-made Mouse Itgb7/Ly69 siRNA oligo Duplex16421MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo699405Pre-made Cynomolgus/Rhesus macaque ITGB7 siRNA oligo Duplex699405Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101099982Pre-made Cat/Feline ITGB7 siRNA oligo Duplex101099982Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo477598Pre-made Dog/Canine ITGB7 siRNA oligo Duplex477598Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo514031Pre-made Bovines/Cattle ITGB7 siRNA oligo Duplex514031Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100063747Pre-made Equine/Horse ITGB7 siRNA oligo Duplex100063747Equine/HorseIn-vitro grade; in-vivo gradeDetail


Integrin Beta 7/ITGB7 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T14065-AbHumanAnti-Human Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T14065-AbRatAnti-Rat Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T14065-AbMouseAnti-Mouse Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T14065-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T14065-AbCat/FelineAnti-Cat/Feline Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T14065-AbDog/CanineAnti-Dog/Canine Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T14065-AbBovines/CattleAnti-Bovines/Cattle Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T14065-AbEquine/HorseAnti-Equine/Horse Integrin Beta 7/ITGB7 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Integrin Beta 7/ITGB7 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T14065-AgHumanHuman Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T14065-AgRatRat Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T14065-AgMouseMouse Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T14065-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T14065-AgCat/FelineCat/Feline Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T14065-AgDog/CanineDog/Canine Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T14065-AgBovines/CattleBovines/Cattle Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T14065-AgEquine/HorseEquine/Horse Integrin Beta 7/ITGB7 VLP (virus-like particle)HEK293Products Developing