Explore RAB7A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T14030
|
| Target Name |
RAB7A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7879
|
| Gene ID |
100050015 (Equus caballus), 101085959 (Felis catus), 19349 (Mus musculus), 29448 (Rattus norvegicus) 404007 (Canis lupus familiaris), 509970 (Bos taurus), 707280 (Macaca mulatta), 7879 (Homo sapiens)
|
| Target Alternative Names |
CMT2B,PRO2706,RAB7,RAB7A,Rab7,Rab7a,Ras-related protein Rab-7a
|
| Uniprot Accession |
P51150,P09527,P18067,Q3T0F5,P51149
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Phagosome, Amoebiasis, Tuberculosis
|
| Gene Ensembl |
ENSECAG00000012559, ENSMUSG00000079477, ENSCAFG00845019242, ENSMMUG00000001798, ENSG00000075785
|
Pre-made viral vector of RAB7A cDNA Clones/ORF Plasmid
RAB7A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7879 | Pre-made Human RAB7A/RAB7/CMT2B siRNA oligo Duplex | 7879 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29448 | Pre-made Rat Rab7a/Rab7 siRNA oligo Duplex | 29448 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19349 | Pre-made Mouse Rab7/Rab7a siRNA oligo Duplex | 19349 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707280 | Pre-made Cynomolgus/Rhesus macaque RAB7A siRNA oligo Duplex | 707280 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085959 | Pre-made Cat/Feline RAB7A siRNA oligo Duplex | 101085959 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404007 | Pre-made Dog/Canine RAB7A/RAB7 siRNA oligo Duplex | 404007 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509970 | Pre-made Bovines/Cattle RAB7A siRNA oligo Duplex | 509970 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050015 | Pre-made Equine/Horse RAB7A siRNA oligo Duplex | 100050015 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RAB7A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T14030-Ab | Human | Anti-Human RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T14030-Ab | Rat | Anti-Rat RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T14030-Ab | Mouse | Anti-Mouse RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T14030-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T14030-Ab | Cat/Feline | Anti-Cat/Feline RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T14030-Ab | Dog/Canine | Anti-Dog/Canine RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T14030-Ab | Bovines/Cattle | Anti-Bovines/Cattle RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T14030-Ab | Equine/Horse | Anti-Equine/Horse RAB7A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RAB7A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T14030-Ag | Human | Human RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T14030-Ag | Rat | Rat RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T14030-Ag | Mouse | Mouse RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T14030-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T14030-Ag | Cat/Feline | Cat/Feline RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T14030-Ag | Dog/Canine | Dog/Canine RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T14030-Ag | Bovines/Cattle | Bovines/Cattle RAB7A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T14030-Ag | Equine/Horse | Equine/Horse RAB7A recombinant protein | Mammalian cell | Detail |