Explore S1PR1/EDG1/CD363 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
| Target ID |
GM-T13852
|
| Target Name |
S1PR1/EDG1/CD363
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1901
|
| Gene ID |
100050049 (Equus caballus), 101091218 (Felis catus), 13609 (Mus musculus), 1901 (Homo sapiens)
281135 (Bos taurus), 29733 (Rattus norvegicus), 490138 (Canis lupus familiaris), 716813 (Macaca mulatta)
|
| Target Alternative Names |
CD363,CHEDG1,D1S3362,ECGF1,EDG-1,EDG1,Edg1,Endothelial differentiation G-protein coupled receptor 1,Lpb1,S1P receptor 1,S1P1,S1PR1,S1p,S1p1,S1pr1,Sphingosine 1-phosphate receptor 1,Sphingosine 1-phosphate receptor Edg-1 (S1P receptor Edg-1)
|
| Uniprot Accession |
O08530,P21453,Q5E9P3,P48303
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000011626, ENSMUSG00000045092, ENSG00000170989, ENSBTAG00000005990, ENSMMUG00000042059
|
| Target Classification |
GPCR
|
Pre-made viral vector of S1PR1/EDG1/CD363 cDNA Clones/ORF Plasmid
S1PR1/EDG1/CD363 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1901 | Pre-made Human S1PR1/EDG1/S1P1 siRNA oligo Duplex | 1901 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29733 | Pre-made Rat S1pr1/Edg1 siRNA oligo Duplex | 29733 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13609 | Pre-made Mouse S1pr1/S1p/Edg1 siRNA oligo Duplex | 13609 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716813 | Pre-made Cynomolgus/Rhesus macaque S1PR1/EDG1 siRNA oligo Duplex | 716813 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091218 | Pre-made Cat/Feline S1PR1 siRNA oligo Duplex | 101091218 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490138 | Pre-made Dog/Canine S1PR1/EDG1 siRNA oligo Duplex | 490138 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281135 | Pre-made Bovines/Cattle S1PR1/EDG1/S1P1 siRNA oligo Duplex | 281135 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050049 | Pre-made Equine/Horse S1PR1/EDG1 siRNA oligo Duplex | 100050049 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
S1PR1/EDG1/CD363 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13852-Ab | Human | Anti-Human S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13852-Ab | Rat | Anti-Rat S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13852-Ab | Mouse | Anti-Mouse S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13852-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13852-Ab | Cat/Feline | Anti-Cat/Feline S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13852-Ab | Dog/Canine | Anti-Dog/Canine S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T13852-Ab | Bovines/Cattle | Anti-Bovines/Cattle S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T13852-Ab | Equine/Horse | Anti-Equine/Horse S1PR1/EDG1/CD363 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
S1PR1/EDG1/CD363 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13852-Ag | Human | Human S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T13852-Ag | Rat | Rat S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T13852-Ag | Mouse | Mouse S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T13852-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T13852-Ag | Cat/Feline | Cat/Feline S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T13852-Ag | Dog/Canine | Dog/Canine S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T13852-Ag | Bovines/Cattle | Bovines/Cattle S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T13852-Ag | Equine/Horse | Equine/Horse S1PR1/EDG1/CD363 VLP (virus-like particle) | HEK293 | Products Developing |
