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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T13644
|
| Target Name |
SSTR3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6753
|
| Gene ID |
100069706 (Equus caballus), 101096494 (Felis catus), 171044 (Rattus norvegicus), 20607 (Mus musculus) 481272 (Canis lupus familiaris), 518585 (Bos taurus), 6753 (Homo sapiens), 696585 (Macaca mulatta)
|
| Target Alternative Names |
SS-3-R,SS3-R,SS3R,SSR-28,SST3,SSTR,SSTR3,Smstr-3,Smstr28,Smstr3,Somatostatin receptor type 3,Sstr3,sst3
|
| Uniprot Accession |
P30936,P30935,P32745
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000059043, ENSMUSG00000044933, ENSCAFG00845007442, ENSBTAG00000055328, ENSG00000278195, ENSMMUG00000018853
|
| Target Classification |
GPCR
|
Pre-made viral vector of SSTR3 cDNA Clones/ORF Plasmid
SSTR3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6753 | Pre-made Human SSTR3/SS3R/SST3 siRNA oligo Duplex | 6753 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171044 | Pre-made Rat Sstr3/SSTR/Smstr28 siRNA oligo Duplex | 171044 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20607 | Pre-made Mouse Sstr3/sst3/Smstr3 siRNA oligo Duplex | 20607 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696585 | Pre-made Cynomolgus/Rhesus macaque SSTR3 siRNA oligo Duplex | 696585 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096494 | Pre-made Cat/Feline SSTR3 siRNA oligo Duplex | 101096494 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481272 | Pre-made Dog/Canine SSTR3 siRNA oligo Duplex | 481272 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo518585 | Pre-made Bovines/Cattle SSTR3 siRNA oligo Duplex | 518585 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069706 | Pre-made Equine/Horse SSTR3 siRNA oligo Duplex | 100069706 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SSTR3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13644-Ab | Human | Anti-Human SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13644-Ab | Rat | Anti-Rat SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13644-Ab | Mouse | Anti-Mouse SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13644-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13644-Ab | Cat/Feline | Anti-Cat/Feline SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13644-Ab | Dog/Canine | Anti-Dog/Canine SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T13644-Ab | Bovines/Cattle | Anti-Bovines/Cattle SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T13644-Ab | Equine/Horse | Anti-Equine/Horse SSTR3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SSTR3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13644-Ag | Human | Human SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T13644-Ag | Rat | Rat SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T13644-Ag | Mouse | Mouse SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T13644-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T13644-Ag | Cat/Feline | Cat/Feline SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T13644-Ag | Dog/Canine | Dog/Canine SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T13644-Ag | Bovines/Cattle | Bovines/Cattle SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T13644-Ag | Equine/Horse | Equine/Horse SSTR3 VLP (virus-like particle) | HEK293 | Products Developing |