Explore ILK gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
| Target ID |
GM-T13616
|
| Target Name |
ILK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3611
|
| Gene ID |
100070066 (Equus caballus), 101092790 (Felis catus), 16202 (Mus musculus), 170922 (Rattus norvegicus)
3611 (Homo sapiens), 476836 (Canis lupus familiaris), 540207 (Bos taurus), 709944 (Macaca mulatta)
|
| Target Alternative Names |
ESTM24,HEL-S-28,ILK,ILK-1,ILK-2,Ilk,Inactive integrin-linked kinase,P59,Scaffold protein ILK,p59ILK
|
| Uniprot Accession |
O55222,Q99J82,Q13418,Q3SWY2
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
PPAR signaling pathway, Axon guidance, Focal adhesion, Endometrial cancer
|
| Gene Ensembl |
ENSECAG00000007599, ENSMUSG00000030890, ENSG00000166333, ENSCAFG00845008689, ENSBTAG00000000696, ENSMMUG00000007741
|
Pre-made viral vector of ILK cDNA Clones/ORF Plasmid
ILK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3611 | Pre-made Human ILK/P59/ILK-1 siRNA oligo Duplex | 3611 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170922 | Pre-made Rat Ilk/ILK-1/ILK-2 siRNA oligo Duplex | 170922 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16202 | Pre-made Mouse Ilk/ILK-1/ILK-2 siRNA oligo Duplex | 16202 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709944 | Pre-made Cynomolgus/Rhesus macaque ILK siRNA oligo Duplex | 709944 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092790 | Pre-made Cat/Feline ILK siRNA oligo Duplex | 101092790 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476836 | Pre-made Dog/Canine ILK siRNA oligo Duplex | 476836 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540207 | Pre-made Bovines/Cattle ILK/ILK-1/ILK-2 siRNA oligo Duplex | 540207 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070066 | Pre-made Equine/Horse ILK siRNA oligo Duplex | 100070066 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ILK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13616-Ab | Human | Anti-Human ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13616-Ab | Rat | Anti-Rat ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13616-Ab | Mouse | Anti-Mouse ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13616-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13616-Ab | Cat/Feline | Anti-Cat/Feline ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13616-Ab | Dog/Canine | Anti-Dog/Canine ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T13616-Ab | Bovines/Cattle | Anti-Bovines/Cattle ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T13616-Ab | Equine/Horse | Anti-Equine/Horse ILK monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ILK VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13616-Ag | Human | Human ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T13616-Ag | Rat | Rat ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T13616-Ag | Mouse | Mouse ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T13616-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T13616-Ag | Cat/Feline | Cat/Feline ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T13616-Ag | Dog/Canine | Dog/Canine ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T13616-Ag | Bovines/Cattle | Bovines/Cattle ILK VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T13616-Ag | Equine/Horse | Equine/Horse ILK VLP (virus-like particle) | HEK293 | Products Developing |
