Explore ALDH5A1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T13259
|
| Target Name |
ALDH5A1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7915
|
| Gene ID |
100067559 (Equus caballus), 101088238 (Felis catus), 214579 (Mus musculus), 291133 (Rattus norvegicus)
488246 (Canis lupus familiaris), 532724 (Bos taurus), 707902 (Macaca mulatta), 7915 (Homo sapiens)
|
| Target Alternative Names |
6330403E24Rik,ALDH5A1,Ahd-1,Ahd1,Aldehyde dehydrogenase family 5 member A1,Aldh5a1,D630032B01Rik,NAD(+)-dependent succinic semialdehyde dehydrogenase,SSADH,SSDH,Ssadh,Ssdh1,Succinate-semialdehyde dehydrogenase,mitochondrial
|
| Uniprot Accession |
Q8BWF0,P51650,P51649
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000020590, ENSMUSG00000035936, ENSCAFG00845018965, ENSBTAG00000021902, ENSMMUG00000019368, ENSG00000112294
|
| Target Classification |
|
ALDH5A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7915 | Pre-made Human ALDH5A1/SSDH/SSADH siRNA oligo Duplex | 7915 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo291133 | Pre-made Rat Aldh5a1/Ssadh siRNA oligo Duplex | 291133 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo214579 | Pre-made Mouse Aldh5a1/Ahd1/Ahd-1 siRNA oligo Duplex | 214579 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707902 | Pre-made Cynomolgus/Rhesus macaque ALDH5A1 siRNA oligo Duplex | 707902 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088238 | Pre-made Cat/Feline ALDH5A1 siRNA oligo Duplex | 101088238 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488246 | Pre-made Dog/Canine ALDH5A1 siRNA oligo Duplex | 488246 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532724 | Pre-made Bovines/Cattle ALDH5A1 siRNA oligo Duplex | 532724 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067559 | Pre-made Equine/Horse ALDH5A1 siRNA oligo Duplex | 100067559 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ALDH5A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13259-Ab | Human | Anti-Human ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13259-Ab | Rat | Anti-Rat ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13259-Ab | Mouse | Anti-Mouse ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13259-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13259-Ab | Cat/Feline | Anti-Cat/Feline ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13259-Ab | Dog/Canine | Anti-Dog/Canine ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T13259-Ab | Bovines/Cattle | Anti-Bovines/Cattle ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T13259-Ab | Equine/Horse | Anti-Equine/Horse ALDH5A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
ALDH5A1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13259-Ag | Human | Human ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T13259-Ag | Rat | Rat ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T13259-Ag | Mouse | Mouse ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T13259-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T13259-Ag | Cat/Feline | Cat/Feline ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T13259-Ag | Dog/Canine | Dog/Canine ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T13259-Ag | Bovines/Cattle | Bovines/Cattle ALDH5A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T13259-Ag | Equine/Horse | Equine/Horse ALDH5A1 recombinant protein | Mammalian cell | Detail |
