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Target
sublocation: Introcelluar Protein.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]
| Target ID |
GM-T13201
|
| Target Name |
CA1/CA-I
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
759
|
| Gene ID |
101094399 (Felis catus), 12346 (Mus musculus), 310218 (Rattus norvegicus), 487031 (Canis lupus familiaris)
703701 (Macaca mulatta), 759 (Homo sapiens)
|
| Target Alternative Names |
CA-I,CA1,CAB,Ca1,Car-1,Car1,Carbonate dehydratase I,Carbonic anhydrase 1,Carbonic anhydrase B (CAB),Carbonic anhydrase I (CA-I),Cyanamide hydratase CA1,HEL-S-11
|
| Uniprot Accession |
P13634,B0BNN3,P00916,P00915
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Dent disease, Malignant neoplasm of bladder
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSMUSG00000027556, ENSCAFG00845017135, ENSMMUG00000014383, ENSG00000133742
|
Pre-made viral vector of CA1/CA-I cDNA Clones/ORF Plasmid
CA1/CA-I siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo759 | Pre-made Human CA1/CAB/CA-I siRNA oligo Duplex | 759 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo310218 | Pre-made Rat Car1/Ca1/CA-I siRNA oligo Duplex | 310218 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12346 | Pre-made Mouse Car1/Ca1/Car-1 siRNA oligo Duplex | 12346 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703701 | Pre-made Cynomolgus/Rhesus macaque CA1/CA-I siRNA oligo Duplex | 703701 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094399 | Pre-made Cat/Feline CA1 siRNA oligo Duplex | 101094399 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487031 | Pre-made Dog/Canine CA1 siRNA oligo Duplex | 487031 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
CA1/CA-I antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13201-Ab | Human | Anti-Human CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T13201-Ab | Rat | Anti-Rat CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T13201-Ab | Mouse | Anti-Mouse CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T13201-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T13201-Ab | Cat/Feline | Anti-Cat/Feline CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T13201-Ab | Dog/Canine | Anti-Dog/Canine CA1/CA-I monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CA1/CA-I recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13201-Ag | Human | Human CA1/CA-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T13201-Ag | Rat | Rat CA1/CA-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T13201-Ag | Mouse | Mouse CA1/CA-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T13201-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CA1/CA-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T13201-Ag | Cat/Feline | Cat/Feline CA1/CA-I recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T13201-Ag | Dog/Canine | Dog/Canine CA1/CA-I recombinant protein | Mammalian cell | Detail |
