Explore WNT5A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| Target ID |
GM-T13175
|
| Target Name |
WNT5A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7474
|
| Gene ID |
100059157 (Equus caballus), 101080694 (Felis catus), 22418 (Mus musculus), 484721 (Canis lupus familiaris)
530005 (Bos taurus), 64566 (Rattus norvegicus), 705692 (Macaca mulatta), 7474 (Homo sapiens)
|
| Target Alternative Names |
8030457G12Rik,Protein Wnt-5a,WNT5A,Wnt-5a,Wnt5a,hWNT5A
|
| Uniprot Accession |
P22725,Q9QXQ7,P41221
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Wnt signaling pathway, Axon guidance, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Melanogenesis, Cushing syndrome, Alzheimer disease, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000008830, ENSMUSG00000021994, ENSCAFG00845026417, ENSBTAG00000020221, ENSMMUG00000061281, ENSG00000114251
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of WNT5A cDNA Clones/ORF Plasmid
WNT5A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7474 | Pre-made Human WNT5A/hWNT5A siRNA oligo Duplex | 7474 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64566 | Pre-made Rat Wnt5a siRNA oligo Duplex | 64566 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22418 | Pre-made Mouse Wnt5a/Wnt-5a/8030457G12Rik siRNA oligo Duplex | 22418 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705692 | Pre-made Cynomolgus/Rhesus macaque WNT5A siRNA oligo Duplex | 705692 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080694 | Pre-made Cat/Feline WNT5A siRNA oligo Duplex | 101080694 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484721 | Pre-made Dog/Canine WNT5A siRNA oligo Duplex | 484721 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530005 | Pre-made Bovines/Cattle WNT5A siRNA oligo Duplex | 530005 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059157 | Pre-made Equine/Horse WNT5A siRNA oligo Duplex | 100059157 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
WNT5A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T13175-Ab | Human | Anti-Human WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T13175-Ab | Rat | Anti-Rat WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T13175-Ab | Mouse | Anti-Mouse WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T13175-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T13175-Ab | Cat/Feline | Anti-Cat/Feline WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T13175-Ab | Dog/Canine | Anti-Dog/Canine WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T13175-Ab | Bovines/Cattle | Anti-Bovines/Cattle WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T13175-Ab | Equine/Horse | Anti-Equine/Horse WNT5A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
WNT5A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T13175-Ag | Human | Human WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T13175-Ag | Rat | Rat WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T13175-Ag | Mouse | Mouse WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T13175-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T13175-Ag | Cat/Feline | Cat/Feline WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T13175-Ag | Dog/Canine | Dog/Canine WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T13175-Ag | Bovines/Cattle | Bovines/Cattle WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T13175-Ag | Equine/Horse | Equine/Horse WNT5A VLP (virus-like particle) | HEK293 | Products Developing |
