GNRHR Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore GNRHR gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]

Target ID GM-T12475
Target Name GNRHR
Gene Group ldentifer
(Target Gene ID in Homo species)
2798
Gene ID 100033874 (Equus caballus), 101088838 (Felis catus), 14715 (Mus musculus), 2798 (Homo sapiens)
281798 (Bos taurus), 403718 (Canis lupus familiaris), 711577 (Macaca mulatta), 81668 (Rattus norvegicus)
Target Alternative Names GNRHR,Gnrhr,HH7,GRHR,LRHR,LHRHR,GNRHR1,GnRH-R,GH1,Lhrhr
Uniprot Accession O18821,Q01776,P30968,P32236,Q9MZI6,Q8SPZ1,P30969
Uniprot Entry Name
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target
Disease cancer
Disease from KEGG Neuroactive ligand-receptor interaction, GnRH signaling pathway
Gene Ensembl ENSECAG00000005763, ENSMUSG00000029255, ENSG00000109163, ENSBTAG00000000438, ENSCAFG00845008435, ENSMMUG00000003779
Target Classification GPCR, Checkpoint-Immuno Oncology


Pre-made viral vector of GNRHR cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002105Human GNRHR/GNRHR1/GRHR Lentivirus plasmidNM_0004062798HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002105Human GNRHR/GNRHR1/GRHR Lentivirus particleNM_0004062798HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


GNRHR siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo2798Pre-made Human GNRHR/HH7/GRHR siRNA oligo Duplex2798HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo81668Pre-made Rat Gnrhr/GH1/Lhrhr siRNA oligo Duplex81668RatIn-vitro grade; in-vivo gradeDetail
pGMoligo14715Pre-made Mouse Gnrhr siRNA oligo Duplex14715MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo711577Pre-made Cynomolgus/Rhesus macaque GNRHR/GnRH-R siRNA oligo Duplex711577Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101088838Pre-made Cat/Feline GNRHR siRNA oligo Duplex101088838Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403718Pre-made Dog/Canine GNRHR siRNA oligo Duplex403718Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281798Pre-made Bovines/Cattle GNRHR siRNA oligo Duplex281798Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100033874Pre-made Equine/Horse GNRHR siRNA oligo Duplex100033874Equine/HorseIn-vitro grade; in-vivo gradeDetail


GNRHR antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T12475-AbHumanAnti-Human GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T12475-AbRatAnti-Rat GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T12475-AbMouseAnti-Mouse GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T12475-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T12475-AbCat/FelineAnti-Cat/Feline GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T12475-AbDog/CanineAnti-Dog/Canine GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T12475-AbBovines/CattleAnti-Bovines/Cattle GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T12475-AbEquine/HorseAnti-Equine/Horse GNRHR monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


GNRHR VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T12475-AgHumanHuman GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T12475-AgRatRat GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T12475-AgMouseMouse GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T12475-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T12475-AgCat/FelineCat/Feline GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T12475-AgDog/CanineDog/Canine GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T12475-AgBovines/CattleBovines/Cattle GNRHR VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T12475-AgEquine/HorseEquine/Horse GNRHR VLP (virus-like particle)HEK293Products Developing