Explore Gamma Cystathionase/CTH gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
| Target ID |
GM-T12241
|
| Target Name |
Gamma Cystathionase/CTH
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1491
|
| Gene ID |
100053614 (Equus caballus), 101083282 (Felis catus), 107869 (Mus musculus), 1491 (Homo sapiens)
24962 (Rattus norvegicus), 479991 (Canis lupus familiaris), 539159 (Bos taurus), 696664 (Macaca mulatta)
|
| Target Alternative Names |
0610010I13Rik,CGL,CSE,CTH,Cth,Cys3,Cystathionine gamma-lyase,Cysteine desulfhydrase,Cysteine-protein sulfhydrase,Gamma Cystathionase,Gamma-cystathionase,Homocysteine desulfhydrase
|
| Uniprot Accession |
Q8VCN5,P32929,P18757,Q58DW2
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000015050, ENSMUSG00000028179, ENSG00000116761, ENSBTAG00000014791, ENSMMUG00000019326
|
| Target Classification |
|
Pre-made viral vector of Gamma Cystathionase/CTH cDNA Clones/ORF Plasmid
Gamma Cystathionase/CTH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1491 | Pre-made Human CTH/CGL/CSE siRNA oligo Duplex | 1491 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24962 | Pre-made Rat Cth/CGL/CSE siRNA oligo Duplex | 24962 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107869 | Pre-made Mouse Cth/CGL/CSE siRNA oligo Duplex | 107869 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696664 | Pre-made Cynomolgus/Rhesus macaque CTH siRNA oligo Duplex | 696664 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083282 | Pre-made Cat/Feline CTH siRNA oligo Duplex | 101083282 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479991 | Pre-made Dog/Canine CTH siRNA oligo Duplex | 479991 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539159 | Pre-made Bovines/Cattle CTH siRNA oligo Duplex | 539159 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053614 | Pre-made Equine/Horse CTH siRNA oligo Duplex | 100053614 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Gamma Cystathionase/CTH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T12241-Ab | Human | Anti-Human Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T12241-Ab | Rat | Anti-Rat Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T12241-Ab | Mouse | Anti-Mouse Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T12241-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T12241-Ab | Cat/Feline | Anti-Cat/Feline Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T12241-Ab | Dog/Canine | Anti-Dog/Canine Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T12241-Ab | Bovines/Cattle | Anti-Bovines/Cattle Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T12241-Ab | Equine/Horse | Anti-Equine/Horse Gamma Cystathionase/CTH monoclonal antibody | mab | Therapeutics Target antibody | Detail |
Gamma Cystathionase/CTH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T12241-Ag | Human | Human Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T12241-Ag | Rat | Rat Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T12241-Ag | Mouse | Mouse Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T12241-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T12241-Ag | Cat/Feline | Cat/Feline Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T12241-Ag | Dog/Canine | Dog/Canine Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T12241-Ag | Bovines/Cattle | Bovines/Cattle Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T12241-Ag | Equine/Horse | Equine/Horse Gamma Cystathionase/CTH recombinant protein | Mammalian cell | Detail |
